64-section multidetector CT angiography for evaluation of intracranial aneurysms: comparison with 3D rotational angiography
64-section multidetector CT angiography for evaluation of intracranial aneurysms: comparison with 3D rotational angiography
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DOI：
10.1177/0284185113506138
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发表时间：
2014-09-01
期刊：
影响因子：
1.3
通讯作者：
Xie, Peng
中科院分区：
文献类型：
--
作者：
Li, Qi;Lv, Fajin;Xie, Peng
背景资料：目的：评价64层CT血管造影（CTA）与新的金标准三维数字减影血管造影（3D DSA）对颅内动脉瘤的诊断价值。评估动脉瘤的位置、大小和形状，并与3D DSA结果进行比较。结果：以3D DSA为参考标准，对118例患者进行64层CTA检查，共检出145个动脉瘤，其中145个动脉瘤的检出率为100%。在这145个动脉瘤中，64节CTA检测到118名患者的139个动脉瘤。CTA检测动脉瘤的敏感性为95.8%。所有漏诊的动脉瘤均为多发动脉瘤患者的非病因性极小动脉瘤。结论：与新的金标准3D DSA相比，64层CTA对颅内动脉瘤的诊断具有更高的敏感性和特异性。它可以很容易地用作颅内动脉瘤的筛查成像方法。
Background: To assess the diagnostic performance of 64-section computed tomography angiography (CTA) for detection of cerebral aneurysms by comparison with the new gold standard three-dimensional (3D) digital subtraction angiography (DSA).Material and Methods: A total of 128 patients who underwent both 64-section CTA and 3D DSA for suspected intracranial aneurysms were included. The location, size, and shape of the aneurysm were assessed and compared with 3D DSA results. The sensitivity, specificity, positive and negative predictive values of 64-section CTA were calculated by using 3D DSA as reference standard.Results: According to the reference standard, a total of 145 aneurysms were detected at 3D DSA in 118 patients. Of these 145 aneurysms, 64-section CTA detected 139 aneurysms in 118 patients. The sensitivity of CTA for detection of aneurysm was 95.8% on a per-aneurysm basis. All missed aneurysms were non-causative very small aneurysms in patients harboring multiple aneurysms. On a per-patient basis, the sensitivity, specificity, positive and negative predictive values were 100%.Conclusion: Compared with the new gold standard 3D DSA, 64-section CTA offers high sensitivity and specificity for detection of intracranial aneurysms. It could be readily used as a screening imaging method for detection of intracranial aneurysms.