BONE-PLATES AND SCREWS OF BIOABSORBABLE POLY (L-LACTIDE) - AN ANIMAL PILOT-STUDY
BONE-PLATES AND SCREWS OF BIOABSORBABLE POLY (L-LACTIDE) - AN ANIMAL PILOT-STUDY
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DOI：
10.1016/s0266-4356(89)80004-x
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发表时间：
1989-12-01
影响因子：
1.8
通讯作者：
JANSEN, HWB
中科院分区：
文献类型：
--
作者：
BOS, RRM;ROZEMA, FR;JANSEN, HWB
聚l -丙交酯是一种乳酸（PLAA）聚合物，具有极高的分子量（.hivin）。Mv等于1乘以。106)已在严格控制的条件下合成，从而产生具有优异机械性能的新型微孔材料。用PLLA加工的骨板和螺钉固定绵羊2例人工下颌骨骨折，采用特殊设计的骨夹。骨折愈合顺利，未见骨痂形成。PLLA钢板和螺钉在足够长的时间内具有良好的稳定性，使骨折正常愈合。在人类身上的应用似乎是合理的。
Poly (L-lactide), a polymer of lactic acid (PLAA), with an extremely high molecular weight (.hivin.Mv up to 1 .times. 106) has been synthesised under strictly controlled conditions resulting in a new microporous material with excellent mechanical properties. Bone-plates and screws machined from PLLA were used for fixation of two artificial mandibular fractures in sheep effected by a specially designed bone clamp. Fracture healing was uneventful without visible callus formation. Plates and screws of PLLA gave good stability over a sufficiently long period to enable normal fracture healing. Application in humans seems to be justified.