Effect of body mass index on overnight oximetry for the diagnosis of steep apnea
Effect of body mass index on overnight oximetry for the diagnosis of steep apnea
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DOI：
10.1016/j.rmed.2003.11.009
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发表时间：
2004-05-01
影响因子：
4.3
通讯作者：
Shinohara, T
中科院分区：
文献类型：
--
作者：
Nakano, H;Ikeda, T;Shinohara, T
夜间血氧饱和度测定广泛用于筛查陡峭呼吸暂停低通气综合征（SAHS）。已知呼吸暂停事件时的去饱和程度受肥胖程度的影响。我们假设血氧测定法对SAHS的诊断能力受到肥胖程度的影响，共对424例因可能的SAHS而转诊的连续患者进行了研究。根据体重指数（BMI）将受试者分为正常体重、超重和肥胖三组。采用多导睡眠图的呼吸暂停低通气指数（大于或等于15 h（-1））作为诊断金标准。ODI 2/3/4（临界值为2%/3%/4%）对正常体重组、超重组和肥胖组的敏感性/特异性分别为54%/100%、83%/97%和98%/78%（P < 0.05）。
Overnight oximetry is widely used for screening for the steep apnea-hypopnea syndrome (SAHS). The degree of desaturation at an apnea event is known to be affected by the degree of obesity. We hypothesized that the diagnostic ability of oximetry for SAHS is affected by the degree of obesity.A total of 424 consecutive patients referred for possible SAHS were studied. The subjects were classified into three groups of normal-weight, overweight and obese based on the body mass index (BMI). The apnea-hypopnea index ( greater than or equal to 15 h(-1)) by polysomnography was used as the diagnostic gold standard. Oximetry data were automatically analyzed to calculate the oxygen desaturation index (ODI2/3/4:at 2%/3%/4% threshold).The diagnostic abilities of the ODI were different in the three BMI-groups at a given cutoff value, e.g. the sensitivity/specificity of ODI4 (cutoff = 15) were 54%/100%, 83%/97%, and 98%/78% for the normal-weight, overweight and obese groups, respectively (P