CD154 polymorphism in Spanish populations.: Differences in the allelic distribution between Canary Islanders and Peninsulars
CD154 polymorphism in Spanish populations.: Differences in the allelic distribution between Canary Islanders and Peninsulars
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DOI：
10.1046/j.1365-2370.2000.00220.x
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发表时间：
2000-06-01
期刊：
影响因子：
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通讯作者：
García-Laorden, I
中科院分区：
文献类型：
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作者：
Citores, MJ;Pérez-Aciego, P;García-Laorden, I
CD154 基因在 3' 非翻译区包含一个二核苷酸重复 (CA)n。描述了来自加那利群岛和半岛这两个具有不同遗传背景的地区的西班牙人群的等位基因分布。发现了两组之间等位基因分布不同的七个等位基因。这代表了一种高度多态性标记，可用于免疫关键分子的遗传研究。
The CD154 gene contains a dinucleotide repeat (CA)n in the 3' untranslated region. Allelic distribution in Spanish populations from two areas with different genetic background, the Canary Islands and Peninsula, are described. Seven alleles with different allelic distribution between the two groups, were found. This represents a highly polymorphic marker, useful for genetic studies on a critical molecule in immunity.