INTRATHORACIC LYMPH-NODE EVALUATION BY CT AND MRI WITH HISTOPATHOLOGIC CORRELATION IN NON-SMALL-CELL BRONCHOGENIC-CARCINOMA
INTRATHORACIC LYMPH-NODE EVALUATION BY CT AND MRI WITH HISTOPATHOLOGIC CORRELATION IN NON-SMALL-CELL BRONCHOGENIC-CARCINOMA
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DOI：
10.1016/0899-7071(90)90116-s
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发表时间：
1990-03-01
期刊：
影响因子：
2.1
通讯作者：
ODONOVAN, PB
中科院分区：
文献类型：
--
作者：
GEORGIAN, D;RICE, TW;ODONOVAN, PB
使用计算机断层扫描 (CT) 和磁共振成像 (MRI) 对 20 名非小细胞支气管癌患者的胸内淋巴结肿大进行了前瞻性研究。 CT和MRI结果与103个淋巴结的手术组织病理学结果相关。根据淋巴结尺寸（使用 1 厘米截止值），两种成像方式都无法准确预测淋巴结的组织病理学。 CT的敏感性为21%，特异性为95%，总体准确性为85%； MRI 的敏感性为 14%，特异性为 97%，总体准确性为 85%。此外，术前 CT 和 MRI 分别仅检测到 17% 和 14% 的切除淋巴结。综上所述，CT和MRI测量的淋巴结大小对于预测淋巴结的良恶性是不准确的。即使胸部 CT 或 MRI 扫描“阴性”，也可能出现淋巴结肿大。
Twenty patients with non-small cell bronchogenic carcinoma were prospectively studied for intrathoracic lymphadenopathy using computed tomography (CT) and magnetic resonance imaging (MRI). The CT and MRI results were correlated with the surgical histopathology results of 103 harvested lymph nodes. Based on node dimension (utilizing a 1-cm cutoff value), neither imaging modality was accurate in predicting the histopathology of the nodes. CT had a sensitivity of 21%, specificity of 95%, and an overall accuracy of 85%; MRI had a sensitivity of 14%, specificity of 97%, and an overall accuracy of 85%. Moreover, CT and MRI detected preoperatively only 17% and 14%, respectively, of the harvested nodes. In summary, lymph node sizes measured by CT and MRI are inaccurate in predicting the benignity or malignancy of lymph nodes. Lymphadenopathy can be present even with a "negative" CT or MRI scan of the thorax.