Applications of Microfluidics in Quantitative Biology
Applications of Microfluidics in Quantitative Biology
复制标题
微流控在定量生物学中的应用
DOI：
10.1002/biot.201700170
复制
发表时间：
2018-05-01
影响因子：
4.7
通讯作者：
Huang, Shuqiang
中科院分区：
文献类型：
--
作者：
Bai, Yang;Gao, Meng;Huang, Shuqiang
定量生物学致力于利用定量推理和先进的工程技术，使生物学更可预测。微流体技术作为一种新兴技术，提供了新的方法来精确控制小规模的流体条件，并以高通量和定量的方式收集数据。在这篇综述中，作者介绍了基于两大类（基于通道的微流体和基于液滴的微流体）的微流体在定量生物学中的相关应用及其典型特征。我们还设想了一些其他的微流控技术，这些技术现在可能还没有在定量生物学中使用，但在不久的将来会有很大的潜力。
Quantitative biology is dedicated to taking advantage of quantitative reasoning and advanced engineering technologies to make biology more predictable. Microfluidics, as an emerging technique, provides new approaches to precisely control fluidic conditions on small scales and collect data in high‐throughput and quantitative manners. In this review, the authors present the relevant applications of microfluidics to quantitative biology based on two major categories (channel‐based microfluidics and droplet‐based microfluidics), and their typical features. We also envision some other microfluidic techniques that may not be employed in quantitative biology right now, but have great potential in the near future.