Hippocampal size positively correlates with verbal IQ in male children
Hippocampal size positively correlates with verbal IQ in male children
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DOI：
10.1002/hipo.20282
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发表时间：
2007-01-01
期刊：
影响因子：
3.5
通讯作者：
Amaral, David G.
中科院分区：
文献类型：
--
作者：
Schumann, Cynthia Mills;Hamstra, Julia;Amaral, David G.
从历史上看，有许多人认为大脑的大小与其处理信息的能力有关。然而，关于儿童和青少年中哪些特定的大脑区域有助于这种相关性，我们知之甚少。这项研究评估了8-18岁典型发育男性儿童的智力与各种大脑结构大小之间的关系。磁共振成像（MRI）扫描用于测量大脑、大脑灰质和白色物质、小脑、杏仁核和海马的体积。灰质和海马体积与全量表和言语智商显著相关。由于海马与言语智商密切相关，但与表现智商无关，我们的研究结果强化了海马参与陈述性和语义学习的假设，这对言语智商的贡献比表现智商更显着。鉴于大量的证据表明，环境引起的海马结构的变化，一个悬而未决的问题是，这种关系是否反映了遗传决定的个体差异或学习诱导的可塑性。(C)2007 Wiley-Liss，Inc.
Historically, there have been numerous proposals that the size of the brain correlates with its capacity to process information. Little is known, however, about which specific brain regions contribute to this correlation in children and adolescents. This study evaluated the relationship between intelligence and the size of various brain structures in typically developing male children 8-18 yrs of age. Magnetic resonance imaging (MRI) scans were used to measure the volume of the cerebrum, cerebral gray and white matter, cerebellum, amygdala, and hippocampus. Gray matter and hippocampal volume significantly correlated with full scale and verbal IQ. Since the hippocampus strongly correlated with verbal but not performance IQ, our findings reinforce the hypothesis that the hippocampus is involved in declarative and semantic learning, which contributes more notably to verbal IQ, than to performance IQ. Given the substantial evidence for environmentally induced changes in hippocampal structure, an unresolved issue is whether this relationship reflects genetically determined individual variation or learning induced plasticity. (C) 2007 Wiley-Liss, Inc.