A novel electrochemical sensor based on Cu@Ni/MWCNTs nanocomposite for simultaneous determination of guanine and adenine
A novel electrochemical sensor based on Cu@Ni/MWCNTs nanocomposite for simultaneous determination of guanine and adenine
复制标题
一种基于Cu@Ni/MWCNTs纳米复合材料的新型电化学传感器，用于同时测定鸟嘌呤和腺嘌呤
DOI：
10.1016/j.bios.2017.11.051
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发表时间：
2018-04-15
影响因子：
12.6
通讯作者：
Li, Yingchun
中科院分区：
文献类型：
--
作者：
Wang, Dongyang;Huang, Bintong;Li, Yingchun
基于多壁碳纳米管和铜镍杂化纳米颗粒（Cu@Ni/MWCNTs）的复合，构建了一种新型的电化学传感平台，用于鸟嘌呤（G）和腺嘌呤（A）的同时检测。采用透射电子显微镜（TEM）和X射线能谱（EDS）对Ni/MWCNTs和Cu@Ni/MWCNTs纳米复合材料进行了表征。在pH3.0的磷酸盐缓冲溶液中，用循环伏安法（CV）和微分脉冲伏安法（DPV）研究了G和A在修饰电极上的电化学行为。在最佳条件下，电信号在5.0 - 180 μ M和8.0 - 150 μ M的浓度范围内呈线性，同时测定G和A的检测限分别低至0.35 μ M和0.56 μ M（S/N = 3）。此外，线性浓度范围分别为1.0-180 μ M和2.0-150 μ M，G和A的检测限分别为0.17 μ M和0.33 μ M（S/N = 3）。该传感器已成功地用于定量G和A在真实的样品。Cu@ Ni/多壁碳纳米管复合材料可作为电化学传感器的候选材料，在广泛的领域发挥重要作用。
A novel electrochemical sensing platform based on combination of multi-walled carbon nanotubes and copper nickel hybrid nanoparticles (Cu@Ni/MWCNTs) was developed for simultaneous detection of guanine (G) and adenine (A). The Ni/MWCNTs and Cu@Ni/MWCNTs nanocomposites were characterized by transmission electron microscopy (TEM) and energy-dispersive X-ray spectroscopy (EDS). The electrochemical behaviors of G and A on the modified electrode were explored by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) in phosphate buffer with pH 3.0. Under the optimal conditions, electrical signals were linear over the concentration ranges from 5.0 to 180 mu M and 8.0 to 150 mu M for simultaneous determination G and A with the detection limit as low as 0.35 mu M and 0.56 mu M (S/N = 3), respectively. Furthermore, linear concentration ranges in individual determination are 1.0-180 mu M and 2.0-150 mu M with detection limits of 0.17 mu M and 0.33 mu M (S/N = 3) for G and A, respectively. The sensor was successfully used to quantify G and A in real samples. The Cu@ Ni/MWCNTs composite presented here can serve as a promising candidate for developing electrochemical sensor devices and plays an important role in widespread fields.