Management of cutaneous dermatomyositis
Management of cutaneous dermatomyositis
复制标题
DOI：
10.1111/j.1529-8019.2012.01491.x
复制
发表时间：
2012-03-01
影响因子：
3.6
通讯作者：
Vleugels, Ruth Ann
中科院分区：
文献类型：
--
作者：
Lam, Christina;Vleugels, Ruth Ann
皮肌炎（DM）传统上被归类为一种特发性炎症性肌病，以肌无力和特征性皮肤表现为特征。在没有肌无力临床证据的情况下出现皮肤表现的患者被归类为临床上无肌病性DM。与皮肤发现相关的症状可能特别使人衰弱，并且肌肉和皮肤疾病之间存在对治疗的不一致反应。已经描述了各种治疗药物和治疗方法，无论是皮肤和皮外表现;然而，在这种疾病的对照研究的缺乏导致在解释现有数据的局限性。在这篇综述中，重点是特别放在总结目前的文献管理皮肤糖尿病。此外，提出了一种治疗皮肤病的算法方法。
Dermatomyositis (DM) is traditionally classified as an idiopathic inflammatory myopathy distinguished by muscle weakness and characteristic cutaneous findings. Patients presenting with the skin manifestations in the absence of clinical evidence of muscle weakness are categorized as clinically amyopathic DM. The symptoms associated with the cutaneous findings can be particularly debilitating, and a discordant response to therapy exists between muscle and skin disease. Various therapeutic agents and treatment approaches have been described, both for the cutaneous and extracutaneous manifestations; however, a paucity of controlled studies in this disease leads to limitations in interpreting the available data. In this review, emphasis is placed specifically on summarizing the current literature regarding management of cutaneous DM. In addition, an algorithmic approach to treatment of skin disease is presented.