Learning Curve for Intracranial Angioplasty and Stenting in Single Center
Learning Curve for Intracranial Angioplasty and Stenting in Single Center
复制标题
单中心颅内血管成形术和支架置入术的学习曲线。
DOI：
10.1002/ccd.25038
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发表时间：
2014-01-01
影响因子：
2.3
通讯作者：
Liu, Xinfeng
中科院分区：
文献类型：
--
作者：
Cai, Qiankun;Li, Yongkun;Liu, Xinfeng
ObjectiveTo identify the specific caseload to overcome learning curve effect based on data from consecutive patients treated with Intracranial Angioplasty and Stenting (IAS) in our center.BackgroundThe Stenting and Aggressive Medical Management for Preventing Recurrent Stroke and Intracranial Stenosis trial was prematurely terminated owing to the high rate of periprocedural complications in the endovascular arm. To date, there are no data available for determining the essential caseload sufficient to overcome the learning effect and perform IAS with an acceptable level of complications.MethodsBetween March 2004 and May 2012, 188 consecutive patients with 194 lesions who underwent IAS were analyzed retrospectively. The outcome variables used to assess the learning curve were periprocedural complications (included transient ischemic attack, ischemic stroke, vessel rupture, cerebral hyperperfusion syndrome, and vessel perforation). Multivariable logistic regression analysis was employed to illustrate the existence of learning curve effect on IAS. A risk-adjusted cumulative sum chart was performed to identify the specific caseload to overcome learning curve effect.ResultsThe overall rate of 30-days periprocedural complications was 12.4% (24/194). After adjusting for case-mix, multivariate logistic regression analysis showed that operator experience was an independent predictor for periprocedural complications. The learning curve of IAS to overcome complications in a risk-adjusted manner was 21 cases.ConclusionsOperator's level of experience significantly affected the outcome of IAS. Moreover, we observed that the amount of experience sufficient for performing IAS in our center was 21 cases. (c) 2013 Wiley Periodicals, Inc.
