Choline acetyltransferase activity in murine thymus
Choline acetyltransferase activity in murine thymus
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小鼠胸腺中胆碱乙酰转移酶的活性
DOI：
10.1002/jnr.490310221
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发表时间：
1992
影响因子：
4.2
通讯作者：
A. Rossi
中科院分区：
文献类型：
--
作者：
M. A. Tria;G. Vantini;M. G. Fiori;A. Rossi
小鼠胸腺已被证明含有胆碱能受体和乙酰胆碱酯酶活性。在目前的研究中，我们研究了胆碱乙酰转移酶在这个器官中的存在，它负责乙酰胆碱的合成。本文报道的结果表明：(1)胸腺在出生当天就已经存在相当数量的酶；(2)它的表达受到发育的调节；(3)小鼠(2周龄)和成年(6周龄)小鼠的胸腺萎缩。注射氢化可的松2天后，仅幼鼠的胆碱乙酰转移酶活性显著降低。
Murine thymus has been demonstrated to contain both cholinergic receptors and acetylcholinesterase activity. In the present study we have investigated the presence of the enzyme choline acetyltransferase in this organ, which is responsible for the synthesis of acetylcholine. Results reported here demonstrate that (1) an appreciable amount of the enzyme is already present in the thymus on the day of birth; (2) its expression is developmentally regulated; and (3) thymic atrophy, induced in young (2‐week‐old) and adult (6‐week‐old) mice by i.p. injection of hydrocortisone for 2 days, is accompanied by significant reduction of choline acetyltransferase activity only in young mice.
淋巴器官的去甲肾上腺素能交感神经支配。
DOI：
--
发表时间：
1988
期刊：
Progress in allergy
影响因子：
--
作者：
Felten,SY;Felten,DL;Bellinger,DL;Carlson,SL;Ackerman,KD;Madden,KS;Olschowka,JA;Livnat,S
通讯作者：
Livnat,S