The effects of an exercise intervention on executive function among overweight adults with obstructive sleep apnea.
The effects of an exercise intervention on executive function among overweight adults with obstructive sleep apnea.
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运动干预对患有阻塞性睡眠呼吸暂停的超重成人执行功能的影响。
DOI：
10.1007/s41105-022-00433-1
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发表时间：
2023
影响因子：
1.1
通讯作者：
Dobrosielski,DevonA
中科院分区：
文献类型：
--
作者：
Kubitz,KarlaA;Park,Hyunjeong;Patil,SusheelP;Papandreou,Christopher;Dobrosielski,DevonA
阻塞性睡眠呼吸暂停（OSA）与执行功能较差有关。本研究探讨了综合运动干预对轻度和中度至重度OSA超重成年人执行功能的影响。参与者年龄在30至65岁之间，体重指数（BMI）在27至42 kg/m2之间，参加了为期6周的锻炼计划。标准化多导睡眠图记录方法提供总的呼吸暂停低通气指数（AHI）和低氧血症水平。执行功能使用NIH Flanker抑制控制测试进行评估。次极量平板运动试验评价心肺功能。基线总AHI在5和14.9事件/h之间的参与者被归类为轻度OSA，基线总AHI 15 ≥事件/h的参与者被归类为中度至重度OSA。15名参与者完成了18次锻炼。在基线时，观察到OSA类别之间的睡眠特征有显著差异，但健身或执行功能没有显著差异。Wilcoxon符号秩检验显示，仅在中度至重度类别中，侧链检验的中值显著增加，z= 2.429，p < 0.015，η2= 0.737。六周的锻炼改善了中度至重度OSA超重个体的执行功能，但对轻度OSA患者没有改善。
Obstructive sleep apnea (OSA) is associated with poorer executive function. This study examined the effects of a comprehensive exercise intervention on executive function in overweight adults with mild and moderate-to-severe OSA. Participants aged between 30 and 65 years, with a body mass index (BMI) ranging from 27 to 42 kg/m2, participated in a 6-week exercise program. Standardized polysomnographic recording methods provided total Apnea–Hypopnea Index (AHI) and level of hypoxemia. Executive function was assessed using the NIH Toolbox Flanker Inhibitory Control Test. A submaximal treadmill exercise test evaluated cardiorespiratory fitness. Participants with baseline total AHI between 5 and 14.9 events/h were classified as mild OSA and participants with baseline total AHI 15 ≥ events/h were classified as moderate-to-severe OSA. Fifteen participants completed 18 exercise sessions. Significant differences between OSA categories at baseline were observed for sleep characteristics, but not for fitness or executive function. Wilcoxon signed rank tests showed significant increases in median values for the Flanker Test in the moderate-to-severe category only,z= 2.429,p< 0.015,η2= 0.737. Six weeks of exercise improved executive function in overweight individuals with moderate-to-severe OSA, but not in those with mild OSA.