Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model.
Optical coherence tomography through a rigid borescope applied to quantification of articular cartilage thickness in a porcine knee model.
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DOI：
10.1364/ol.44.005590
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发表时间：
2019-11-15
期刊：
影响因子：
3.6
通讯作者：
Wax A
中科院分区：
文献类型：
--
作者：
Jelly ET;Steelman ZA;Wax A
对于简单、稳健、适用于普通外科手术的OCT传送方案的需求尚未得到满足。为了在狭窄的形状因素中传输光束，光学管道镜提供了一个有吸引力的潜在解决方案。我们提出了一种使用适合低成本OCT引擎的手持式刚性内窥镜实现光学相干断层扫描（OCT）内窥镜传输的方法。该系统减少了扫描仪的远端轮廓，使系统能够在其他难以进入的区域应用。这种设计的临床潜力通过关节软骨厚度的实时量化来证明，关节软骨厚度是骨关节炎期间关节健康的主要生物标志物。该平台有潜力在关节镜手术中使用OCT进行实时反馈。
There exists an unmet need for an OCT delivery scheme which is simple, robust, and applicable to general surgical applications. To deliver the beam in a narrow form factor, optical borescopes present an attractive potential solution. We present a method for enabling endoscopic delivery of optical coherence tomography (OCT) using a hand-held rigid borescope adapted to a low-cost OCT engine. The system reduces the distal profile of the scanner, enabling application of the system in otherwise hard-to-access regions. The clinical potential of this design is demonstrated through real-time quantification of articular cartilage thickness, a primary biomarker of joint health during osteoarthritis. This platform has the potential to enable use of OCT for real-time feedback during arthroscopic surgery.