Economic evaluation of a randomised controlled trial for anorexia nervosa in adolescents

Economic evaluation of a randomised controlled trial for anorexia nervosa in adolescents
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DOI:
10.1192/bjp.bp.107.036806
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发表时间:
2007-11-01
影响因子:
10.5
通讯作者:
Gowers, Simon G.
Gowers, Simon G.
中科院分区:
医学1区
文献类型:
--
作者:
Byford, Sarah;Barrett, Barbara;Gowers, Simon G.

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背景患有神经性厌食症的年轻人经常被送往医院接受治疗。以及被破坏的学校,家庭和社会生活,住院治疗是昂贵的,但成本效益的证据是lacking.Aims成本效益分析的三个治疗策略为青少年与anorexia nervosa.Method英国多中心随机对照试验比较住院精神病治疗,专科门诊治疗和普通门诊治疗。结果和成本评估基线,I和2 years.Results有167名年轻人在试验中。2年时,三组之间的临床结局无统计学显著差异。专家门诊组在2年随访期间的费用(平均总费用26磅738)低于住院组(34磅53 1)和普通门诊治疗组(40磅794),但这一结果没有统计学意义。探索的不确定性与三种治疗的成本和效果表明,专科门诊治疗具有最高的概率是cost-effectiveness.Conclusions成本效益的基础上,这些结果支持提供专科门诊服务的青少年神经性厌食症。
Background Young people with anorexia nervosa are often admitted to hospital for treatment. As well as being disruptive to school, family and social life, in-patient treatment is expensive, yet cost-effectiveness evidence is lacking.Aims Cost-effectiveness analysis of three treatment strategies for adolescents with anorexia nervosa.Method UK multicentre randomised, controlled trial comparing in-patient psychiatric treatment, specialist outpatient treatment and general out-patient treatment. Outcomes and costs assessed at baseline, I and 2 years.Results There were 167 young people in the trial. There were no statistically significant differences in clinical outcome between the three groups at 2 years. The specialist out-patient group was less costly over the 2-year follow-up (mean total cost 26 pound 738) than the in-patient (34 pound 53 1) and general out-patient treatment (40 pound 794) groups, but this result was not statistically significant. Exploration of the uncertainty associated with the costs and effects of the three treatments suggests that specialist out-patient treatment has the highest probability of being cost-effective.Conclusions On the basis of cost-effectiveness, these results support the provision of specialist out-patient services for adolescents with anorexia nervosa.