Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players.
Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players.
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DOI：
10.1080/10446670410001722159
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发表时间：
2005-03
影响因子：
--
通讯作者：
Keen, Carl L
中科院分区：
文献类型：
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作者：
Fraga, Cesar G;Actis-Goretta, Lucas;Ottaviani, Javier I;Carrasquedo, Fernando;Lotito, Silvina B;Lazarus, Sheryl;Schmitz, Harold H;Keen, Carl L
食用富含某些类黄酮的饮食，包括黄烷醇 亚类，与血管疾病风险降低有关。我们 评估了定期消费（14天）的含黄烷醇的 牛奶巧克力（FCMC）或可可脂巧克力（CBC）对相关变量的影响 血管疾病风险、氧化应激和体力活动。28个自由生活， 年轻（18-20岁）男子足球运动员每天消耗105 g FCMC (168毫克黄烷醇）或CBC（<5毫克黄烷醇），作为正常饮食的一部分。 FCMC的消耗与舒张压的降低显著相关， 血压（-5 mmHg）、平均血压（-5 mmHg）、血浆胆固醇 (-11%）、LDL-胆固醇（~ 15%）、丙二醛（~ 12%）、尿酸盐（~ 11%）和乳酸盐 脱氢酶（LDH）活性（-11%）和维生素E/胆固醇增加 （升百分之十二）。这些变量的相关变化与CBC无关 消费未观察到（-）-表儿茶素血浆水平的变化 在分析空腹血液样本后。总而言之，FCMC消费量 与常与心血管疾病相关的几个变量的变化相关 健康和氧化应激。存在大量的 FCMC中的黄烷醇可能是这些结果的促成因素之一。
The consumption of a diet rich in certain flavonoids, including the flavanol sub-class, has been associated with a reduced risk for vascular disease. We evaluated the effects of the regular consumption (14 d) of a flavanol-containing milk chocolate (FCMC) or cocoa butter chocolate (CBC) on variables related to vascular disease risk, oxidative stress and physical activity. Twenty-eight free-living, young (18–20 years old) male soccer players consumed daily 105 g of FCMC (168 mg of flavanols) or CBC (<5 mg of flavanols), as part of their normal diet. The consumption of FCMC was significantly associated with a decrease in diastolic blood pressure (-5 mm Hg), mean blood pressure (-5 mm Hg), plasma cholesterol (-11%), LDL-cholesterol (-15%), malondialdehyde (-12%), urate (-11%) and lactate dehydrogenase (LDH) activity (-11%), and an increase in vitamin E/cholesterol (+12%). No relevant changes in these variables were associated with CBC consumption. No changes in the plasma levels of (-)-epicatechin were observed following analysis of fasting blood samples. In conclusion, FCMC consumption was associated with changes in several variables often associated with cardiovascular health and oxidant stress. The presence of significant quantities of flavanols in FCMC is likely to have been one of the contributing factors to these results.