MEMO plus : Efficacy, Durability and Effect of Cognitive Training and Psychosocial Intervention in Individuals with Mild Cognitive Impairment
MEMO plus : Efficacy, Durability and Effect of Cognitive Training and Psychosocial Intervention in Individuals with Mild Cognitive Impairment
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DOI：
10.1111/jgs.15192
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发表时间：
2018-04-01
影响因子：
6.3
通讯作者：
Gauthier, Serge
中科院分区：
文献类型：
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作者：
Belleville, Sylvie;Hudon, Carol;Gauthier, Serge
背景/目的由于缺乏设计良好的随机对照试验，认知训练对轻度认知障碍（MCI）患者的疗效尚未达成共识。目的是评估记忆训练对MCI患者认知功能的影响及其持久性，并评估这种影响是否适用于日常生活，以及是否可以从心理干预中获得积极效果。随机盲对照试验。设置蒙特利尔老年大学和魁北克圣心大学研究中心。老年人会议研究对象被随机分为认知训练组、社会心理干预组和无接触对照组。在8个2小时的sessions.MeasurementOutcome措施的小组提供了即时和延迟复合性能记忆分数，心理健康（抑郁，焦虑，幸福），和干预的泛化效果（策略使用在日常生活中，在复杂的日常生活活动的困难，记忆投诉）。测试前进行培训，并立即，3个月，和6个月后training.ResultsParticipants在认知训练条件下提高延迟复合记忆分数和日常生活中的策略使用。在3个月和6个月随访评估时保持改善。在社会心理和无接触conditions.ConclusionCognitive培训的参与者没有表现出任何显着improvementation.ConclusionCognitive培训提高了健忘MCI的人的记忆。这种效果持续了6个月，学习的策略在日常生活中使用。认知训练是促进MCI患者认知功能的有效途径。
Background/ObjectivesThere is no consensus on the efficacy of cognitive training in persons with mild cognitive impairment (MCI) because of the paucity of well-designed randomized controlled trials. The objective was to assess the effect of memory training on the cognitive functioning of persons with MCI and its durability and to evaluate whether this effect generalizes to daily life and whether positive effects could be obtained from psychosocial intervention.DesignSingle-blind randomized controlled trial.SettingResearch centers of the Institut Universitaire de Geriatrie de Montreal and Institut Universitaire en Sante Mentale de Quebec.ParticipantsOlder adults meeting criteria for amnestic MCI (N=145).InterventionParticipants were randomized to cognitive training, a psychosocial intervention, or a no-contact control condition. Interventions were provided in small groups in eight 2-hour sessions.MeasurementOutcome measures were immediate and delayed composite performance memory scores, psychological health (depression, anxiety, well-being), and generalization effects of the intervention (strategy use in everyday life, difficulties in complex activities of daily living, memory complaints). Testing was administered before training and immediately, 3months, and 6months after training.ResultsParticipants in the cognitive training condition improved on the delayed composite memory score and on strategy use in everyday life. Improvement was maintained at the 3- and 6-month follow-up assessments. Participants in the psychosocial and no-contact conditions did not show any significant improvement.ConclusionCognitive training improves the memory of persons with amnestic MCI. The effect persists over a 6-month period, and learned strategies are used in everyday life. Cognitive training is a valid way to promote cognition in MCI.See related editorial by .