Inspiratory flow limitation during sleep in pre-eclampsia: comparison with normal pregnant and nonpregnant women
Inspiratory flow limitation during sleep in pre-eclampsia: comparison with normal pregnant and nonpregnant women
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DOI：
10.1183/09031936.01.00053501
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发表时间：
2001-10-01
影响因子：
24.3
通讯作者：
McNicholas, WT
中科院分区：
文献类型：
--
作者：
Connolly, G;Razak, ARA;McNicholas, WT
自我报告打鼾在怀孕期间很常见，特别是在患有先兆子痫的女性中。对先兆子痫女性睡眠时吸气流量受限的患病率进行了客观评估，并与正常妊娠和非妊娠女性进行了比较，将15名先兆子痫女性与15名来自妊娠三个月的女性以及15名匹配的非妊娠对照女性（总研究人群，75名受试者）进行了比较。所有受试者均整夜监测呼吸、氧饱和度和血压（BP）。没有一组有临床意义的睡眠呼吸暂停综合征的证据，但先兆子痫患者有更多的时间（31 ± 8.4%的睡眠时间，平均SD）有吸气流量受限的证据，而妊娠晚期受试者有15.5 ± 2.3%，
Self-reported snoring is common in pregnancy, particularly in females with pre-eclampsia. The prevalence of inspiratory flow limitation during sleep in preeclamptic females was objectively assessed and compared with normal pregnant and nonpregnant females.Fifteen females with pre-eclampsia were compared to 15 females from each of the three trimesters of pregnancy, as well as to 15 matched nonpregnant control females (total study population, 75 subjects). All subjects had overnight monitoring of respiration, oxygen saturation, and blood pressure (BP).No group had evidence of a clinically significant sleep apnoea syndrome, but patients with pre-eclampsia spent substantially more time (31 +/-8.4%, of sleep period time, mean SD) with evidence of inspiratory flow limitation compared to 15.5 +/-2.3% in third trimester subjects and