Prevalence of depression and anxiety in patients requesting physicians' aid in dying: cross sectional survey.

Prevalence of depression and anxiety in patients requesting physicians' aid in dying: cross sectional survey.
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DOI:
10.1136/bmj.a1682
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发表时间:
2008-10-07
期刊:
BMJ (Clinical research ed.)
影响因子:
--
通讯作者:
Dobscha SK
Dobscha SK
中科院分区:
其他
文献类型:
--
作者:
Ganzini L;Goy ER;Dobscha SK

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目的了解临终病人在寻求医生帮助时抑郁和焦虑的发生情况。设计横断面调查。背景位于美国俄勒冈州。参与者58俄勒冈人,大多数患有癌症或肌萎缩侧索硬化症,他们要么向医生请求死亡援助,要么联系了死亡倡导组织的援助。主要结果测量根据医院焦虑和抑郁量表和精神疾病诊断和统计手册的结构化临床访谈诊断抑郁或焦虑。 结果15名研究参与者符合抑郁的“病例”标准,13名符合焦虑标准。42名患者在研究结束时死亡; 18名患者根据《尊严死亡法》接受了致命药物的处方,9名患者死于致命摄入。15名接受致命药物处方的参与者不符合抑郁症的标准; 3人符合。所有三名抑郁的参与者都在研究访谈的两个月内死于法律的摄入。结论:虽然大多数接受死亡援助的俄勒冈州绝症患者没有抑郁症,但《尊严死亡法》目前的做法可能无法保护一些受抑郁症影响的患者,使其免受致命药物的处方。
Objective To determine the prevalence of depression and anxiety in terminally ill patients pursuing aid in dying from physicians. Design Cross sectional survey. Setting State of Oregon, USA. Participants 58 Oregonians, most terminally ill with cancer or amyotrophic lateral sclerosis, who had either requested aid in dying from a physician or contacted an aid in dying advocacy organisation. Main outcome measures Diagnosis of depression or anxiety according to the hospital anxiety and depression scale and the structured clinical interview for the Diagnostic and Statistical Manual of Mental Disorders. Results 15 study participants met “caseness” criteria for depression, and 13 met criteria for anxiety. 42 patients died by the end of the study; 18 received a prescription for a lethal drug under the Death with Dignity Act, and nine died by lethal ingestion. 15 participants who received a prescription for a lethal drug did not meet criteria for depression; three did. All three depressed participants died by legal ingestion within two months of the research interview. Conclusion Although most terminally ill Oregonians who receive aid in dying do not have depressive disorders, the current practice of the Death with Dignity Act may fail to protect some patients whose choices are influenced by depression from receiving a prescription for a lethal drug.
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