Pseudomonas in the sinks in an intensive care unit: relation to patients.
Pseudomonas in the sinks in an intensive care unit: relation to patients.
复制标题
重症监护病房水槽中的假单胞菌：与患者的关系。
DOI：
10.1136/jcp.37.4.424
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发表时间：
1984
影响因子：
3.4
通讯作者：
R. Weinstein
中科院分区：
文献类型：
--
作者：
M. Levin;B. Olson;C. Nathan;S. Kabins;R. Weinstein
作为ICU患者获得铜绿假单胞菌的7个月前瞻性研究的一部分，在连续6周期间培养内科-外科重症监护病房（ICU）的水槽排水管。分离株进行血清学分型和氨基糖苷类和洗必泰敏感模式。所有11个水槽都含有多种铜绿假单胞菌菌株;一些菌株持续数周，而另一些菌株仅分离一次。56%的水槽分离株对庆大霉素和妥布霉素具有高水平的耐药性，而在患者中未发现菌株。在水槽分离洗必泰耐药性与氨基糖苷类耐药性和洗必泰分配器在水槽的存在。表型相似分离株的恢复顺序表明，水槽是患者在6周内最多2次获得铜绿假单胞菌的来源。我们的研究证实，水槽可能是大量高耐药铜绿假单胞菌的储存库，但很少是ICU患者定植微生物的来源。
Sink drains in a medical-surgical intensive care unit (ICU) were cultured during six consecutive weeks as part of a seven month prospective study of acquisition of Pseudomonas aeruginosa by ICU patients. Isolates were typed serologically and by aminoglycoside and chlorhexidine susceptibility patterns. All 11 sinks contained multiple strains of P aeruginosa; some strains persisted for weeks while others were isolated once. Of the sink isolates 56% had high level resistance to gentamicin and tobramycin whereas none of the strains found in patients. In sink isolates chlorhexidine resistance correlated with aminoglycoside resistance and with the presence of a chlorhexidine dispenser at a sink. The sequence of recovery of phenotypically similar isolates suggested that sinks were the source of at most two acquisitions of P aeruginosa by patients during the six weeks. Our study confirms that sinks may be reservoirs for large numbers of highly resistant P aeruginosa but are rarely the source of organisms colonising patients in our ICU.