Activation of motility and chemotaxis in the spermatozoa: From invertebrates to humans.
Activation of motility and chemotaxis in the spermatozoa: From invertebrates to humans.
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DOI：
10.1111/j.1447-0578.2005.00099.x
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发表时间：
2005-06-01
影响因子：
3.4
通讯作者：
Yoshida, Manabu
中科院分区：
文献类型：
--
作者：
Morisawa, Masaaki;Yoshida, Manabu
精子运动的激活和精子对卵子的趋化行为是受精时精子与卵子之间的第一次交流，了解这一现象不仅是基础生物学进展的前提，也是临床研究进展的前提。仅在少数无脊椎动物、海胆、海鞘和鲱鱼中研究了来自卵子的分子激活精子并将其吸引到卵子的性质，以及精子激活和趋化的分子机制。然而，在包括人类在内的哺乳动物物种中，关于这一现象的知识一直被忽视。本文首先介绍了海洋无脊椎动物精子的激活和趋化作用的研究，并描述了包括人类在内的哺乳动物精子的激活和趋化现象。(Reprod Med Biol 2005；4：101-115)。
Activation of the sperm motility and chemotactic behavior of sperm toward eggs are the first communication between spermatozoa and eggs at fertilization, and understanding of the phenomena is a prerequisite for progress of not only basic biology, but also clinical aspects. The nature of molecules derived from eggs by which sperm are activated and attracted towards the eggs and the molecular mechanisms underlying the sperm activation and chemotaxis have been investigated in only a few invertebrate species, sea urchins, ascidians and herring fish. However, knowledge on this phenomena has been ignored in mammalian species including humans. The current review first introduces the studies on the activation and chemotaxis of sperm in marine invertebrates, and the same phenomena in mammals including humans, are described. (Reprod Med Biol 2005; 4: 101-115).