Interactions between eating disorders and drug abuse
Interactions between eating disorders and drug abuse
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DOI：
10.1097/nmd.0b013e31817d0153
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发表时间：
2008-07-01
影响因子：
1.9
通讯作者：
Herzog, David B.
中科院分区：
文献类型：
--
作者：
Franko, Debra L.;Dorer, David J.;Herzog, David B.
在纵向样本中检查药物滥用和进食障碍之间的关系。在一项前瞻性研究中，对诊断为DSM-IV神经性厌食症（n = 136）或神经性贪食症（n = 110）的女性进行了访谈，并在8.6年内每6-12个月对研究诊断标准药物使用障碍（DUD）进行评估。与预期相反，DUD并不影响从饮食失调中恢复。多变量分析表明，在研究过程中饮酒和自杀企图，以及在研究前因情感障碍住院，预测神经性厌食症的DUD。对于神经性贪食症，多变量预测因子包括研究过程中饮酒的严重程度和贪食症状的严重程度，以及在进入研究之前因非情感性精神障碍住院。饮食失调妇女的药物滥用是临床关注的一个领域，应定期监测。
To examine the relationship between drug abuse and eating disorders in a longitudinal sample. In a prospective study, women diagnosed with either DSM-IV anorexia nervosa (n = 136) or bulimia nervosa (n = 110) were interviewed and assessed for research diagnostic criteria drug use disorder (DUD) every 6-12 months over 8.6 years. Contrary to expectation, DUD did not influence recovery from either eating disorder. Multivariate analyses indicated that alcohol use and suicide attempts over the course of the study, as well as hospitalization for an affective disorder before the study, predicted DUD in anorexia nervosa. For bulimia nervosa, multivariate predictors included the severity of alcohol use and the severity of bulimic symptoms over the course of the study, and a hospitalization before study entry for a nonaffective disorder. Drug abuse in women with eating disorders is an area of clinical concern and should be monitored routinely.