Short- and long-term outcomes of rectal cancer patients with high or improved low ligation of the inferior mesenteric artery.

Short- and long-term outcomes of rectal cancer patients with high or improved low ligation of the inferior mesenteric artery.
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高位或改良低位结扎肠系膜下动脉的直肠癌患者的短期和长期结果。

DOI:
10.1038/s41598-020-72303-0
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发表时间:
2020-09-18
期刊:
影响因子:
4.6
通讯作者:
Su X
Su X
中科院分区:
综合性期刊3区
文献类型:
--
作者:
Zhang C;Chen L;Cui M;Xing J;Yang H;Yao Z;Zhang N;Tan F;Liu M;Xu K;Su X

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腹腔镜直肠癌根治术中肠系膜下动脉(IMA)的结扎部位一直存在争议。回顾性分析2009年1月至2015年12月期间连续接受腹腔镜辅助低位前切除术的直肠癌患者(n = 205)。将患者分为高位结扎组(n = 126)和改良低位结扎组(n = 79)。共有205例直肠癌患者接受了腹腔镜辅助前切除术:高位结扎组126例,改良低位结扎组79例。改良低位结扎组术后排气时间、术后排便时间均优于高位结扎组。各组之间在失血量、手术时间、淋巴结总数、吻合口瘘、术后首次流质饮食时间和术后住院时间方面没有差异。 5 年总生存率 (OS) 也没有差异。与高位结扎相比,改进的低位结扎保证了淋巴结清扫的范围,促进术后胃肠功能的早期恢复,但不增加手术时间、出血风险或吻合口瘘。腹腔镜直肠癌手术中 IMA 的结扎部位可能不会影响肿瘤学结果。
The ligation site of the inferior mesenteric artery (IMA) during laparoscopic radical resection for rectal cancer has been controversial. Consecutive patients (n = 205) with rectal cancer who underwent laparoscopic-assisted low anterior resection from January 2009 to December 2015 were retrospectively analyzed. The patients were divided into high ligation (n = 126) and improved low ligation groups (n = 79). A total of 205 rectal cancer patients underwent laparoscopic assisted anterior resection: 126 patients in the high ligation group and 79 patients in the improved low ligation group. The improved low ligation group was better than the high ligation group in terms of postoperative flatus time and postoperative defecation time. There were no differences between the groups in terms of blood loss, operation time, total number of lymph nodes, anastomotic leakage, postoperative time to first liquid diet and postoperative hospital stay. There were also no differences in 5-year overall survival (OS). Compared to high ligation, the improved low ligation ensures the extent of lymph node dissection, and promotes the early recovery of postoperative gastrointestinal function, but does not increase the operation time, bleeding risk, or anastomotic leakage. A ligation site of the IMA in laparoscopic rectal cancer surgery may not influence oncological outcomes.
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