Material property estimation for tubes and arteries using ultrasound radiation force and analysis of propagating modes
Material property estimation for tubes and arteries using ultrasound radiation force and analysis of propagating modes
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DOI：
10.1121/1.3533735
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发表时间：
2011-03-01
影响因子：
2.4
通讯作者：
Greenleaf, James F.
中科院分区：
文献类型：
--
作者：
Bernal, Miguel;Nenadic, Ivan;Greenleaf, James F.
动脉弹性已被提议作为心血管疾病和死亡率的独立预测因子。薄壳中不同传播模式的识别可用于表征弹性特性。使用超声波辐射力在聚氨酯管壁或切除的猪颈动脉中产生局部机械波。使用脉冲回波超声波跟踪波。使用二维离散快速傅立叶变换对时空信号进行模态分析。这使得两种结构的不同传播模式和色散曲线特征得以可视化。聚氨酯管/动脉安装在金属框架中，嵌入组织模拟明胶中，插管并加压在 10-100 mmHg 范围内。聚氨酯管的 k 空间和色散曲线显示一种传播模式，没有跨壁压力的影响。兰姆波模型的拟合估计聚氨酯管中的杨氏模量约为 560 kPa。动脉杨氏模量在 10 毫米汞柱和 100 毫米汞柱下分别为 72 至 134 kPa。在动脉弥散曲线中观察到的变化表明，这种激发机械波和表征传播模式的方法具有研究动脉弹性的潜力。 (c) 2011 年美国声学学会。 [DOI：10.1121/1.3533735]
Arterial elasticity has been proposed as an independent predictor of cardiovascular diseases and mortality. Identification of the different propagating modes in thin shells can be used to characterize the elastic properties. Ultrasound radiation force was used to generate local mechanical waves in the wall of a urethane tube or an excised pig carotid artery. The waves were tracked using pulse-echo ultrasound. A modal analysis using two-dimensional discrete fast Fourier transform was performed on the time-space signal. This allowed the visualization of different modes of propagation and characterization of dispersion curves for both structures. The urethane tube/artery was mounted in a metallic frame, embedded in tissue-mimicking gelatin, cannulated, and pressurized over a range of 10-100 mmHg. The k-space and the dispersion curves of the urethane tube showed one mode of propagation, with no effect of transmural pressure. Fitting of a Lamb wave model estimated Young's modulus in the urethane tube around 560 kPa. Young's modulus of the artery ranged from 72 to 134 kPa at 10 and 100 mmHg, respectively. The changes observed in the artery dispersion curves suggest that this methodology of exciting mechanical waves and characterizing the modes of propagation has potential for studying arterial elasticity. (c) 2011 Acoustical Society of America. [DOI: 10.1121/1.3533735]