The role of ACL injury in the development of posttraumatic knee osteoarthritis.
The role of ACL injury in the development of posttraumatic knee osteoarthritis.
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DOI：
10.1016/j.csm.2012.08.017
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发表时间：
2013-01
影响因子：
2
通讯作者：
Chu CR
中科院分区：
文献类型：
--
作者：
Friel NA;Chu CR
前十字韧带(ACL)是年轻人中比较常见的一种损伤.前交叉韧带损伤在青少年从事涉及旋转的运动中高发，如足球、足球、篮球和团队手球。年轻女性在参加这些运动时，前交叉韧带受伤的风险是男性的35倍。1-3大多数急性前交叉韧带撕裂患者在受伤时年龄都在30岁以下。因此，前交叉韧带损伤导致早发性骨关节炎(OA)与疼痛、功能受限和生活质量下降有关。4报告的前交叉韧带损伤后创伤性骨关节炎(PTOA)发生率高达87%。5、6相比之下，根据Framingham骨关节炎研究报告，45岁以上的所有成年人的骨性关节炎患病率为19.2%，而约翰斯顿县骨关节炎项目报告的发病率为27.8%。据估计，前交叉韧带断裂会使膝盖老化30岁。1前交叉韧带损伤后PTOA发生率的差异可能与评估患者的方法、不同的手术方法、手术与重建之间的时间间隔以及术后随访时间有关。此外，临床症状并不总是与影像或身体评估相关，导致在前交叉韧带损伤的处理中有许多持续争论的领域。前交叉韧带撕裂的处理范围从非手术治疗到重建手术。重建前交叉韧带的主要目的是恢复膝关节的稳定性，使患者能够恢复受伤前的活动。前交叉韧带重建并不能延缓PTOA的后期发展。研究结果各不相同，报告显示，在接受前交叉韧带重建的患者中，PTOA水平降低、持平或甚至增加。因此，需要更好地了解前交叉韧带损伤后骨性关节炎的发展，以便为制定降低这一人群的骨性关节炎风险的策略提供信息。
The anterior cruciate ligament (ACL) a relatively common injury in young, physically active individuals. ACL injuries are seen at high incidence in adolescents playing sports that involve pivoting, such as football, soccer, basketball, and team handball. Young women have a 35 times higher risk of ACL injury than do men when participating in these sports. 1–3 Most patients with acute ACL tears are younger than 30 at the time of their injury. As such, ACL injuries result in early onset osteoarthritis (OA) were associated with pain, functional limitations, and decreased quality of life. 4 The reported incidence of posttraumatic osteoarthritis (PTOA) following ACL injury as high as 87%. 5, 6 By comparison, the prevalence of OA in all adults older than 45 years of age was 19.2%, as reported by the Framingham Osteoarthritis Study, and 27.8%, as reported by the Johnston County Osteoarthritis Project. 7 It has also been estimated that an ACL rupture ages the knee by 30 years. 1 Variations in the incidence of PTOA may be due to different methods used to evaluate patients, various surgical techniques, the time interval between surgery and reconstruction, and the duration of follow-up after ACL injury. In addition, clinical symptoms do not always correlate with imaging or physical assessments, resulting in many areas of ongoing debate in the management of ACL injuries. Management of a torn ACL ranges from nonoperative treatment to reconstructive surgery. The primary goals of ACL reconstruction are to restore knee stability, allowing the patient to resume his or her preinjury activities. ACL reconstruction has not been shown to delay later development of PTOA. Study results vary, with reports showing decreased, equal, or even increased levels of PTOA in patients who have had ACL reconstruction. As such, there is high need for improved understanding of OA development after ACL injury to inform development of strategies to reduce OA risk in this population.
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DOI：
10.1007/bf01552652
发表时间：
1994-01-01
期刊：
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA
影响因子：
--
作者：
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影响因子：
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DOI：
10.1016/j.arthro.2007.03.094
发表时间：
2007-06-01
影响因子：
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