Nrf2-Mediated Metabolic Reprogramming in Cancer.
Nrf2-Mediated Metabolic Reprogramming in Cancer.
复制标题
Nrf2 介导的癌症代谢重编程
DOI:
10.1155/2018/9304091
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发表时间:
2018
影响因子:
--
通讯作者:
Zhe H
中科院分区:
文献类型:
--
作者:
Wang YY;Chen J;Liu XM;Zhao R;Zhe H
Metabolic reprogramming is one of the hallmarks of cancer. Nrf2 pathway is one of the critical signaling cascades involved in cell defense and survival against oxidative stress. The significance of Nrf2 in cancer metabolism begins to be recognized. In this minireview, we focus on the Nrf2-mediated cancer metabolic reprogramming and intend to highlight the role of Nrf2 in the regulation of malignant transformation, cancer proliferation, and the development of treatment resistance via metabolic adaptations. We hope for the development of noninvasive biomarkers and novel therapeutic approaches for cancer based on Nrf2-directed cancer metabolic reprogramming in the near future.
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DOI:
10.1073/pnas.172398899
发表时间:
2002-09-03
影响因子:
11.1
作者:
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DOI:
10.1006/bbrc.1997.6943
发表时间:
1997-07-18
影响因子:
3.1
作者:
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