BONE MASS IN HIRSUTE WOMEN WITH ANDROGEN EXCESS

BONE MASS IN HIRSUTE WOMEN WITH ANDROGEN EXCESS
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DOI:
10.1111/j.1365-2265.1989.tb02235.x
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发表时间:
1989-03-01
影响因子:
3.2
通讯作者:
FOGELMAN, I
FOGELMAN, I
中科院分区:
医学3区
文献类型:
--
作者:
DIXON, JE;RODIN, A;FOGELMAN, I

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采用双光子吸收法对32例月经过少、雄激素过多的多毛妇女的脊柱和股骨骨质量进行了测量,并与32例月经周期正常的对照妇女的骨质量进行了比较。尽管多毛人群的雌二醇水平显着降低,但骨量没有显着差异。此外,在5名雌二醇水平检测不到的多毛妇女中,骨量没有显着差异。它的结论是,雄激素过剩可以维持正常的骨量,在面对低或检测不到的雌二醇水平。
The spinal and femoral bone mass of 32 hirsute women with oligomenorrhoea and androgen excess was measured using dual photon absorptiometry and compared with the bone mass of 32 control women with regular menstrual cycles. Despite significantly lower estradiol levels in the hirsute population there was no significant difference in the bone mass. Furthermore there was no significant difference in bone mass in five hirsute women with undetectable levels of estradiol. It is concluded that androgen excess can maintain normal bone mass in the face of low or undetectable oestradiol levels.