Predictors of a True Complete Response Among Disappearing Liver Metastases From Colorectal Cancer After Chemotherapy
Predictors of a True Complete Response Among Disappearing Liver Metastases From Colorectal Cancer After Chemotherapy
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DOI：
10.1002/cncr.24912
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发表时间：
2010-03-15
期刊：
影响因子：
6.2
通讯作者：
D'Angelica, Michael.
中科院分区：
文献类型：
--
作者：
Auer, Rebecca C.;White, Rebekah R.;D'Angelica, Michael.
背景：在化疗期间，一些结直肠肝转移（LMs）在序列影像学上消失。这种消失可能代表完全缓解（CR）或化疗期间成像敏感性降低。当前研究的目的是确定消失的LMs （DLMs）的命运和预测真正CR的因素。方法：在2000年至2003年期间，由肝胆外科医生评估的435例患者在考虑切除前接受化疗。纳入标准为
BACKGROUND: During chemotherapy, some colorectal liver metastases (LMs) disappear on serial imaging. This disappearance may represent a complete response (CR) or a reduction in the sensitivity of imaging during chemotherapy. The objective of the current study was to determine the fate of disappearing LMs (DLMs) and the factors that predict a true CR. METHODS: Between 2000 and 2003, 435 patients who were evaluated by hepatobiliary surgeons received chemotherapy before they were considered for resection. Inclusion criteria were