Oxidation of pharmaceuticals during ozonation and advanced oxidation processes
Oxidation of pharmaceuticals during ozonation and advanced oxidation processes
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DOI：
10.1021/es025896h
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发表时间：
2003-03-01
影响因子：
11.4
通讯作者：
Von Gunten, U
中科院分区：
文献类型：
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作者：
Huber, MM;Canonica, S;Von Gunten, U
本研究调查了饮用水处理中应用的传统臭氧化和高级氧化工艺 (AOP) 过程中药物的氧化情况。第一步，在实验室规模实验中确定所选药物与臭氧 (k(O3)) 和 OH 自由基 (k(OH)) 反应的二阶速率常数（括号中为 pH 7 和 T = 20 摄氏度时的表观 k(O3)）：苯扎贝特 (590 +/- 50 M-1 s(-1))、卡马西平（类似于 3 x 10(5)） M-1 s(-1))、地西泮 (0.75 +/- 0.15 M-1 s(-1))、双氯芬酸（类似于 1 X 10(6) M-1 s(-1))、17α-炔雌醇（类似于 3 x 10(6) M-1 s(-1)）、布洛芬 (9.6 +/- 1.0 M-1 s(-1))、碘普罗胺 (5 x 10(4) M-1 s(-1)，表明这些化合物在臭氧化过程中完全转化。 kOH 的值范围为 3.3 至 9.8 x 10(9) M-1 s(-1)。与其他重要的微污染物（例如 MTBE 和莠去津）相比，所选药物与 OH 自由基的反应速度大约快两到三倍。在研究的第二部分中，选定的氧化动力学 在不同天然水中进行的臭氧化实验中对药物进行了研究。可以证明，在纯水溶液中测定的二阶速率常数可用于预测溶解在天然水中的药物的行为。总体而言，可以得出结论，臭氧化和 AOP 是有效去除饮用水中药物的有前途的方法。
This study investigates the oxidation of pharmaceuticals during conventional ozonation and advanced oxidation processes (AOPs) applied in drinking water treatment. In a first step, second-order rate constants for the reactions of selected pharmaceuticals with ozone (k(O3)) and OH radicals (k(OH)) were determined in bench-scale experiments (in brackets apparent k(O3) at pH 7 and T = 20 degreesC): bezafibrate (590 +/- 50 M-1 s(-1)), carbamazepine (similar to3 x 10(5) M-1 s(-1)), diazepam (0.75 +/- 0.15 M-1 s(-1)), diclofenac (similar to1 X 10(6) M-1 s(-1)), 17alpha-ethinylestradiol (similar to3 x 10(6) M-1 s(-1)), ibuprofen (9.6 +/- 1.0 M-1 s(-1)), iopromide (5 x 10(4) M-1 s(-1), indicating that these compounds are completely transformed during ozonation processes. Values for kOH ranged from 3.3 to 9.8 x 10(9) M-1 s(-1). Compared to other important micropollutants such as MTBE and atrazine, the selected pharmaceuticals reacted about two to three times faster with OH radicals. In the second part of the study, oxidation kinetics of the selected pharmaceuticals were investigated in ozonation experiments performed in different natural waters. It could be shown that the second-order rate constants determined in pure aqueous solution could be applied to predict the behavior of pharmaceuticals dissolved in natural waters. Overall it can be concluded that ozonation and AOPs are promising processes for an efficient removal of pharmaceuticals in drinking waters.