Saponins in Tribulus terrestris -: chemistry and bioactivity
Saponins in Tribulus terrestris -: chemistry and bioactivity
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DOI：
10.1007/s11101-005-2833-x
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发表时间：
2005-01-01
影响因子：
7.7
通讯作者：
Dinchev, D.
中科院分区：
文献类型：
--
作者：
Kostova, I.;Dinchev, D.
蒺藜是一种珍贵的药用植物，在世界各地都有广泛的应用。在该植物中经常发现的是替戈配基、新替戈配基、吉托配基、新吉托配基、海柯配基、新海柯配基、薯蓣配基、氯代配基、鲁斯科配基和萨洒皂草配基类型的呋甾烷醇和螺甾烷醇皂苷。还分离出四种泰格配基和薯蓣配基类型的硫酸化皂苷。已发现提取物和甾体皂苷具有多种药理活性。基于T. terrestris用于治疗男性和女性的不育症和性欲障碍，以及用于治疗心脏病。含有T.在美国和欧洲销售有土芥提取物，声称具有一般刺激作用。
Tribulus terrestris is a valuable herb known for its application in the folk medicine in many parts of the world. Furostanol and spirostanol saponins of tigogenin, neotigogenin, gitogenin, neogitogenin, hecogenin, neohecogenin, diosgenin, chlorogenin, ruscogenin and sarsasapogenin type are frequently found in this plant. Four sulphated saponins of tigogenin and diosgenin type are also isolated. Extracts and steroidal saponins have been found to possess various pharmacological activities. Preparations based on the saponin fraction of T. terrestris are used for treatment of infertility and libido disorders in men and women, as well as for treatment of cardiac diseases. Food supplements containing T. terrestris extracts are on sale in USA and Europe with claim of a general stimulating action.