Observational studies: cohort and case-control studies.
Observational studies: cohort and case-control studies.
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DOI：
10.1097/prs.0b013e3181f44abc
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发表时间：
2010-12
影响因子：
3.6
通讯作者：
Chung KC
中科院分区：
文献类型：
--
作者：
Song JW;Chung KC
观察性研究是研究设计的一个重要类别。为了解决整形外科中的一些调查问题，随机对照试验并不总是有指征或符合伦理道德。相反，观察性研究可能是解决这类问题的下一个最佳方法。设计良好的观察性研究已被证明提供与随机对照试验相似的结果，挑战了观察性研究是二流研究的信念。队列研究和病例对照研究是两种主要类型的观察性研究，有助于评估疾病和暴露之间的关联。在这篇综述文章中，我们描述了这些研究设计，方法学问题，并提供了整形外科文献的例子。
Observational studies are an important category of study designs. To address some investigative questions in plastic surgery, randomized controlled trials are not always indicated or ethical to conduct. Instead, observational studies may be the next best method to address these types of questions. Well-designed observational studies have been shown to provide results similar to randomized controlled trials, challenging the belief that observational studies are second-rate. Cohort studies and case-control studies are two primary types of observational studies that aid in evaluating associations between diseases and exposures. In this review article, we describe these study designs, methodological issues, and provide examples from the plastic surgery literature.