Shedding Light on OrganocatalysisLight-Assisted Asymmetric Ion-Pair Catalysis for the Enantioselective Hydrogenation of Pyrylium Ions
Shedding Light on OrganocatalysisLight-Assisted Asymmetric Ion-Pair Catalysis for the Enantioselective Hydrogenation of Pyrylium Ions
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DOI：
10.1002/chem.201300766
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发表时间：
2013-07-22
影响因子：
4.3
通讯作者：
Rueping, Magnus
中科院分区：
文献类型：
--
作者：
Hsiao, Chien-Chi;Liao, Hsuan-Hung;Rueping, Magnus
开发了一种新的光驱动不对称离子对催化程序，用于从容易获得的查尔酮中原位生成吡喃鎓离子进行无金属对映选择性氢化（参见方案）。光辅助布朗斯台德酸催化程序具有广泛的应用范围，并且首次能够以良好的产率和优异的对映选择性获得有价值的 4H-色烯。
A new light‐driven asymmetric ion‐pair catalysis procedure for the metal‐free enantioselective hydrogenation of in situ generated pyrylium ions from readily available chalcones was developed (see scheme). The photo‐assisted Brønsted acid catalyzed procedure has broad scope and allows, for the first time, access to valuable 4H‐chromenes in good yields and with excellent enantioselectivities.