Quantitative analysis of emphysema and airway measurements according to iterative reconstruction algorithms: comparison of filtered back projection, adaptive statistical iterative reconstruction and model-based iterative reconstruction
Quantitative analysis of emphysema and airway measurements according to iterative reconstruction algorithms: comparison of filtered back projection, adaptive statistical iterative reconstruction and model-based iterative reconstruction
复制标题
DOI：
10.1007/s00330-013-3078-5
复制
发表时间：
2014-04-01
影响因子：
5.9
通讯作者：
Shim, Mi-Suk
中科院分区：
文献类型：
--
作者：
Choo, Ji Yung;Goo, Jin Mo;Shim, Mi-Suk
为了评价滤波反投影(FBP)和两种迭代重建(IR)算法对CT图像上肺实质和气道测量的影响，对281例成人胸部CT图像进行了低剂量FBP、自适应统计IR(ASIR)和基于模型的IR(MBIR)重建。比较每个数据集的测量结果：总肺体积、肺气肿指数(EI)、管腔和管壁面积的气道测量值以及平均管壁厚度。阈值为-950HU的EI在三种算法中有显著差异，依次为FBP(2.30%)、AMIR(1.49%)和MBIR(1.20%)(P<；0.01)。三种算法的室壁厚度也有显著差异，FBP(2.09 mm)比ASIR(2.00 mm)和MBIR(1.88 mm)显示的壁厚(P<；0.01)。气道体模分析显示MBIR对气道测量最准确，三种算法显示不同的EIS和管壁厚度，按FBP、ASIR和MBIR的顺序递减。因此，在肺的定量分析中应该注意选择合适的IR算法。越来越多的人使用欧分计算机断层扫描来提供胸腔内结构的客观测量。欧分迭代重建算法会影响肺和呼吸道的定量测量。在纵向分析中，在选择重建算法时应该谨慎。基于欧分模型的迭代重建似乎提供了最准确的气道测量。
To evaluate filtered back projection (FBP) and two iterative reconstruction (IR) algorithms and their effects on the quantitative analysis of lung parenchyma and airway measurements on computed tomography (CT) images.Low-dose chest CT obtained in 281 adult patients were reconstructed using three algorithms: FBP, adaptive statistical IR (ASIR) and model-based IR (MBIR). Measurements of each dataset were compared: total lung volume, emphysema index (EI), airway measurements of the lumen and wall area as well as average wall thickness. Accuracy of airway measurements of each algorithm was also evaluated using an airway phantom.EI using a threshold of -950 HU was significantly different among the three algorithms in decreasing order of FBP (2.30 %), ASIR (1.49 %) and MBIR (1.20 %) (P < 0.01). Wall thickness was also significantly different among the three algorithms with FBP (2.09 mm) demonstrating thicker walls than ASIR (2.00 mm) and MBIR (1.88 mm) (P < 0.01). Airway phantom analysis revealed that MBIR showed the most accurate value for airway measurements.The three algorithms presented different EIs and wall thicknesses, decreasing in the order of FBP, ASIR and MBIR. Thus, care should be taken in selecting the appropriate IR algorithm on quantitative analysis of the lung.aEuro cent Computed tomography is increasingly used to provide objective measurements of intra-thoracic structures.aEuro cent Iterative reconstruction algorithms can affect quantitative measurements of lung and airways.aEuro cent Care should be taken in selecting reconstruction algorithms in longitudinal analysis.aEuro cent Model-based iterative reconstruction seems to provide the most accurate airway measurements.