Unsymmetrical diborane(4) derivatives by copper mediated B-B coupling.
Unsymmetrical diborane(4) derivatives by copper mediated B-B coupling.
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DOI：
10.1039/c8dt00627j
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发表时间：
2018-04
影响因子：
4
通讯作者：
W. Oschmann;C. Borner;Christian Kleeberg
中科院分区：
文献类型：
--
作者：
W. Oschmann;C. Borner;Christian Kleeberg
本发明提供了一种新颖的、通用的和模块化的制备带有两个不同的二醇部分或一个二醇和一个二胺部分的不对称二硼烷（4）衍生物的路线。利用硼亲核试剂与硼亲电试剂反应以建立B-B键的非常基本的方法允许两个单独的硼部分的简单变化。用作亲核硼源的铜（i）硼基络合物容易从市售对称二硼烷（4）衍生物获得，而同样容易获得的卤化硼衍生物用作亲电子试剂。获得了七种以前无法获得的乙硼烷（4）衍生物，并进行了充分的表征，包括单晶X射线结构测定，说明了该方法的广泛范围。
A novel, versatile and modular route to unsymmetrical diborane(4) derivatives bearing either two different diol moieties or one diol and one diamine moiety is presented. Utilising the very basic approach of reacting a boron nucleophile with a boron electrophile to establish the B-B bond allows a simple variation of the two individual boron moieties. The copper(i) boryl complexes used as nucleophilic boron sources are readily accessible from commercially available symmetrical diborane(4) derivatives, whilst equally readily available boron halide derivatives are used as electrophiles. Seven previously inaccessible diborane(4) derivatives were obtained and fully characterised, including single crystal X-ray structure determinations, illustrating the broad scope of the method.