Prevalence of Bronchiectasis in Patients with Chronic Rhinosinusitis in a Tertiary Care Center
Prevalence of Bronchiectasis in Patients with Chronic Rhinosinusitis in a Tertiary Care Center
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DOI：
10.1016/j.jaip.2021.04.054
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发表时间：
2021-08-05
影响因子：
9.4
通讯作者：
Stevens, Whitney W.
中科院分区：
文献类型：
--
作者：
Peters, Anju T.;Bose, Sumit;Stevens, Whitney W.
背景技术背景：尽管慢性鼻窦炎（CRS）与哮喘相关，反之亦然，CRS与其他下呼吸道疾病之间的关联尚未得到充分证实。支气管扩张的特征是气道的永久性损伤，多达45%的支气管扩张患者患有CRS，但CRS患者中支气管扩张的患病率尚不清楚。目的：确定CRS患者中支气管扩张的患病率，并描述支气管扩张和CRS患者的人口统计学和临床特征。方法：通过计算机算法检索鼻窦炎患者的电子病历，并辅以手动病历审查，以识别CRS、哮喘和/或支气管扩张患者。人口统计学和临床特征和抗生素疗程鼻窦手术前和后2年sinusoidal感染获得的手动chartreview.Results：支气管扩张的患病率确定的国际疾病分类，第九次修订代码是CRS患者明显高于哮喘患者（2.3%比1.7%，P <0.003）。同样，基于胸部计算机断层扫描（CT）报告中“支气管扩张”的文本词搜索，接受胸部CT扫描的CRS患者的支气管扩张患病率高于接受胸部CT扫描的哮喘患者（24.3% vs 19.5%; P = 0.005）。CRS合并支气管扩张的患者与无支气管扩张的CRS患者相比，鼻窦手术后鼻窦感染的频率没有降低（P <0.05）。结论：支气管扩张是CRS患者的重要合并症，可能是慢性鼻窦疾病的严重表型。(C)2021年美国过敏、哮喘和免疫学会
BACKGROUND: Whereas chronic rhinosinusitis (CRS) is associated with asthma, and vice versa, the association between CRS and other lower respiratory conditions is not well established. Bronchiectasis is characterized by permanent damage of the airways, and as many as 45% of bronchiectasis patients have CRS, but the prevalence of bronchiectasis among CRS patients is not known.OBJECTIVE: To determine the prevalence of bronchiectasis among CRS patients and to characterize demographic and clinical features of patients with bronchiectasis and CRS.METHODS: Electronic medical records of patients with rhinosinusitis were searched by computer algorithm supplemented with manual chart review to identify patients with CRS, asthma, and/or bronchiectasis. Demographic and clinical features and antibiotic courses for sinopulmonary infections 2 years before and after sinus surgery were obtained by manual chart review.RESULTS: The prevalence of bronchiectasis as determined by International Classification of Diseases, Ninth Revision code was significantly higher in CRS patients than in asthmatic patients (2.3% vs 1.7%; P < .003). Similarly, based on a text word search of "bronchiectasis" in the chest computed tomography (CT) scan reports, patients with CRS who had chest CT scans had a higher prevalence of bronchiectasis than did asthmatic patients with chest CT scans (24.3% vs 19.5%; P = .005). Patients with CRS and concurrent bronchiectasis did not have a reduction in the frequency of sinopulmonary infections after sinus surgery compared with patients with CRS without bronchiectasis (P < .05).CONCLUSIONS: Bronchiectasis is an important comorbidity in patients with CRS and may identify a severe phenotype of chronic sinonasal disease. (C) 2021 American Academy of Allergy, Asthma & Immunology