NOTE: Effects of lateral olfactory tract stimulation on Fos immunoreactivity in vasopressin neurones of the rat piriform cortex
NOTE: Effects of lateral olfactory tract stimulation on Fos immunoreactivity in vasopressin neurones of the rat piriform cortex
复制标题
注: 侧嗅道刺激对大鼠梨状皮层加压素神经元 Fos 免疫反应性的影响
DOI：
10.1111/jne.12637
复制
发表时间：
2018
影响因子：
3.2
通讯作者：
Tsuji C
中科院分区：
文献类型：
--
作者：
Tsuji C
嗅觉信号，包括那些社会气味线索，有强大的行为效应在许多物种，包括人类。在哺乳动物的嗅觉线索的处理是由两个解剖学上不同的途径：主要和辅助嗅觉系统。1-3在辅助嗅觉系统中，信息素在犁鼻器接收，然后在辅助嗅球（AOB）和随后的高级大脑区域（最重要的是内侧杏仁核）处理。4在主嗅觉系统中，气味在主嗅上皮中被记录，然后在主嗅球（MOB）中被处理，随后被前嗅核（AON）、梨状皮质（PC）和皮质杏仁核处理。5，6 PC不仅仅是初级嗅觉中继，在气味感知的感官到更多认知方面发挥着积极作用。神经肽血管加压素，产生于下丘脑和垂体分泌，在电解质和液体稳态中具有关键作用，尽管最近对血管加压素的兴趣主要是其在脑内的功能，特别是其参与社会识别。加压素参与在嗅球7、8和诸如侧隔的脑区域的水平上的社会识别的调节。9，10神经肽也调节社会
Olfactory signals, including those of social odour cues, have powerful behavioural effects in many species, including man. The processing of olfactory cues in mammals is handled by two anatomically distinct pathways: the main and the accessory olfactory systems. 1-3 In the accessory olfactory system, pheromones are received at the vomeronasal organ and then processed at the accessory olfactory bulb (AOB) and, subsequently, higher brain regions, most importantly the medial amygdala. 4 In the main olfactory system, odours are registered at the main olfactory epithelium and then processed at the main olfactory bulb (MOB) and, subsequently, by the anterior olfactory nucleus (AON), the piriform cortex (PC) and the cortical amygdala. 5, 6 The PC is more than a primary olfactory relay and plays an active role from sensory to more cognitive aspects of odour perception. The neuropeptide vasopressin, produced in the hypothalamus and secreted from the pituitary, has a key role in electrolyte and fluid homeostasis, although recent interest in vasopressin has been dominated by its functions within the brain and especially on its involvement in social recognition. Vasopressin is involved in the modulation of social recognition at the level of the olfactory bulbs 7, 8 and brain regions such as the lateral septum. 9, 10 The neuropeptide also regulates social