expa: a program for calculating extreme pathways in biochemical reaction networks
expa: a program for calculating extreme pathways in biochemical reaction networks
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DOI：
10.1093/bioinformatics/bti228
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发表时间：
2005-04-15
期刊：
影响因子：
5.8
通讯作者：
Palsson, BO
中科院分区：
文献类型：
--
作者：
Bell, SL;Palsson, BO
极端路径的集合，即生化反应网络中所有可能的稳态通量图的生成集，可以从化学计量矩阵（反映网络拓扑结构的类入射矩阵）计算。在这里，我们描述了一个众所周知的算法来计算这些途径的实施，并给出了可用软件的功能摘要。
The set of extreme pathways, a generating set for all possible steady-state flux maps in a biochemical reaction network, can be computed from the stoichiometric matrix, an incidence-like matrix reflecting the network topology. Here, we describe the implementation of a well-known algorithm to compute these pathways and give a summary of the features of the available software.