Flexible dispersive liquid-liquid microextraction for on-site sample pre-concentration
Flexible dispersive liquid-liquid microextraction for on-site sample pre-concentration
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用于现场样品预浓缩的灵活分散液-液微萃取
DOI：
10.1080/03067319.2019.1665654
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发表时间：
2019
影响因子：
2.6
通讯作者：
Luo Youqing
中科院分区：
文献类型：
--
作者：
Li Songqing;Han Wentao;Zhao Wanning;Luo Youqing
近年来，现场样品制备技术越来越受到人们的关注。分散液-液微萃取无需离心或有毒有机溶剂，并证明适合于现场提取。本研究开发了一种柔性分散液-液微萃取技术，用于水样的现场预富集。制备包含相分离过滤器的装置。采用聚丙烯纤维填充的相分离过滤器，将乳化体系的萃取相和水相进行手动过滤分离，避免了分散液-液微萃取中通常需要的电动装置。将该装置与基于离子液体的原位分散液液微萃取相结合，开发了一种完全无电的方法。在该过程中，通过离子交换反应形成萃取相1-己基-3-甲基咪唑鎓双[（三氟甲烷）磺酰基]酰亚胺，然后通过过滤与水分离。过滤后，将萃取相洗脱并提交给高效液相色谱-可变波长检测器进行分析。影响萃取性能的参数进行了研究和优化。优化的程序实现了75- 89%的提取回收率。器械内、器械间、日内和日间相对标准偏差均小于4.6%。在2至1000 µg L−1的校准范围内获得了良好的线性（r2> 0.9992）。该方法的检测限为0.41-0.65 µg L−1。由于不需要电子设备和有机分散剂，本方法被证明是绿色，快速，非常灵活的现场制备水样。该装置也有望使其他分散液-液微萃取转化为现场操作。
In recent years, more and more interest has been focused on the on-site sample preparation. Dispersive liquid–liquid microextractions without centrifugation or toxic organic solvent were developed and proved suitable for on-site extraction. In this study, a flexible dispersive liquid–liquid microextraction was developed for on-site water sample pre-concentration. A device containing a phase separation filter was prepared. By means of the phase separation filter packed with hydrophobic nonwoven polypropylene fibre, extraction phase and aqueous phase of the emulsified system were separated by manual filtration, which avoided the electric devices usually required in dispersive liquid–liquid microextractions. Combining the device with ionic liquid-based in situ dispersive liquid–liquid microextraction, a totally electricity-free procedure was developed. During the procedure, the extraction phase 1-hexyl-3-methylimidazolium bis[(trifluoromethane)sulfonyl]imide was formed through an ion exchange reaction, and then separated with water by filtration. After filtration, the extraction phase was eluted and submitted to high-performance liquid chromatography-variable wavelength detector for analysis. Parameters affecting the extraction performance were investigated and optimised. The optimised procedure achieved extraction recoveries of 75–89%. The intra-device, inter-device, intra-day and inter-day relative standard deviations were less than 4.6%. Good linearity (r2> 0.9992) was obtained over the calibration range from 2 to 1000 µg L−1. The limits of detection of the method were in the range of 0.41–0.65 µg L−1. Because electric devices and organic dispersants are not required, the present approach is proved green, fast, and extremely flexible for on-site preparation of water sample. The proposed device is also expected to make other dispersive liquid–liquid microextractions transform into the on-site procedure.