Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study
Association between the combined fat mass and fat-free mass index and hypertension: The Tohoku Medical Megabank Community-based Cohort Study
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DOI：
10.1080/10641963.2021.1925681
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发表时间：
2021-07-08
影响因子：
12.3
通讯作者：
Hozawa, Atsushi
中科院分区：
文献类型：
--
作者：
Takase, Masato;Nakamura, Tomohiro;Hozawa, Atsushi
高体脂率与高血压有关，即使在非肥胖者中也是如此。身体成分的差异可能与高血压有关。脂肪质量指数（fat mass index， FMI）和无脂质量指数（fat-free mass index， FFMI）是人们提出的身体组成指标。本研究旨在探讨FMI联合FFMI与高血压的关系。方法：我们对日本东北部宫城县5058名男性和11842名年龄在bb0 = 20岁的女性进行了横断面研究。FMI和FFMI分别计算为脂肪质量和无脂肪质量除以身高的平方。指数按四分位数划分，并分为16组。高血压定义为随意血压>= 140/90 mmHg和/或自我报告的高血压治疗。采用多变量logistic回归模型，对潜在混杂因素进行校正，评估FMI和FFMI联合使用与高血压的关系。结果在大多数FFMI亚组中，较高的FMI与高血压相关。同样，在大多数FMI亚组中，较高的FFMI与高血压相关。对于男性，最低FMI组的FFMI与高血压之间的关联不显著。结论降低FMI和FFMI可能对预防高血压有重要意义。对于男性，最低FMI组的FFMI与高血压之间的关系可能较弱。
Background A higher body fat percentage is associated with hypertension, even in non-obese individuals. The difference in body composition may be related to hypertension. The fat mass index (FMI) and fat-free mass index (FFMI) are proposed indicators of body composition. This study aimed to examine the relationship of a combination of FMI and FFMI with hypertension. Methods We conducted a cross-sectional study of 5,058 men and 11,842 women aged >= 20 years in the Miyagi Prefecture, northeastern Japan. The FMI and FFMI were calculated as the fat mass and fat-free mass divided by the height squared, respectively. The indices were classified into quartiles and combined into 16 groups. Hypertension was defined as casual blood pressure >= 140/90 mmHg and/or self-reported treatment for hypertension. Multivariable logistic regression models, adjusted for potential confounders, were used to assess the relationship of a combination of FMI and FFMI with hypertension. Results Higher FMI was associated with hypertension in most of the FFMI subgroups. Similarly, a higher FFMI was associated with hypertension in most of FMI subgroups. For men, the association between FFMI and hypertension in the lowest FMI group was not significant. Conclusions Reducing the FMI and FFMI may be important in preventing hypertension. For men, the relationship between the FFMI and hypertension in the lowest FMI group might be weak.