Macular Hole Formation in Fellow Eyes With a Perifoveal Posterior Vitreous Detachment of Patients With a Unilateral Macular Hole
Macular Hole Formation in Fellow Eyes With a Perifoveal Posterior Vitreous Detachment of Patients With a Unilateral Macular Hole
复制标题
DOI：
10.1016/j.ajo.2011.01.011
复制
发表时间：
2011-06-01
影响因子：
4.2
通讯作者：
Hirokawa, Hiroyuki
中科院分区：
文献类型：
--
作者：
Takahashi, Atsushi;Yoshida, Akitoshi;Hirokawa, Hiroyuki
目的：应用光学相干断层扫描(OCT)评估单侧特发性全层黄斑裂孔(MH)患者黄斑裂孔周围玻璃体后脱离(PVD)和早期1期黄斑中心凹内病变的黄斑裂孔形成率。设计：回顾性观察病例系列。结果：在176例单侧全层MH患者中，42例(42只眼)黄斑周围PVD患者被确认为黄斑周围PVD。随访期间，16只眼有黄斑脱离，4只眼有黄斑假性囊肿。黄斑脱离的16只眼中，有9只眼合并黄斑内裂开。随访2年，黄斑中心凹脱离的16只眼中有5只眼(31%)发生第二次全层MH，黄斑脱离合并黄斑内裂孔的9只眼中有5只眼发生第二次全层MH。仅有黄斑中心凹假性囊肿的4只眼中有2只发展为玻璃体中心凹分离，无孔洞形成。结论：黄斑裂孔形成的风险较高，黄斑脱离和黄斑周围PVD可能是高危因素，黄斑脱离和黄斑内裂可能是黄斑裂孔形成的高危因素。《眼科杂志》2011；151：981-989。(C)2011年由Elsevier Inc.保留所有权利。)
Purpose: To estimate the rate of macular hole formation in fellow eyes with a perifoveal posterior vitreous detachment (PVD) and early stage 1 intrafoveal lesions in patients with a unilateral idiopathic full-thickness macular hole (MH) using optical coherence tomography (OCT).DESIGN: Retrospective observational case series.METHODS: Fellow eyes of consecutive patients with a unilateral full-thickness MH were examined on OCT. A subset of fellow eyes with a perifoveal PVD had been followed to investigate the rates of macular hole formation in fellow eyes with early stage 1 intrafoveal lesions.RESULTS: Of 176 patients with a unilateral full-thickness MH, 42 fellow eyes (42 patients) with a perifoveal PVD were identified. During follow-up, a foveolar detachment was seen in 16 eyes, and 4 eyes had a foveal pseudocyst alone. In the 16 eyes with a foveolar detachment, 9 eyes had concurrent inner foveal splits. Within another 2 years of follow-up, OCT showed that 5 of 16 fellow eyes (31%) with a foveolar detachment developed a second full-thickness MH and 5 of 9 fellow eyes with a foveolar detachment and inner foveal splits developed a second full-thickness MH. Two of 4 eyes with a foveal pseudocyst alone developed vitreofoveal separation without hole formation. The remaining 2 eyes with a foveal pseudocyst alone remained stable at the last follow-up visit.CONCLUSIONS: Fellow eyes with a foveolar detachment and a perifoveal PVD may be at high risk, and fellow eyes with a foveolar detachment and inner foveal splits might be at higher risk for progression to macular hole formation. (Am J Ophthalmol 2011;151: 981-989. (C) 2011 by Elsevier Inc. All rights reserved.)