Amygdala response to both positively and negatively valenced stimuli
Amygdala response to both positively and negatively valenced stimuli
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DOI：
10.1097/00001756-200108280-00036
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发表时间：
2001-08-28
期刊：
影响因子：
1.7
通讯作者：
Risinger, RC
中科院分区：
文献类型：
--
作者：
Garavan, H;Pendergrass, JC;Risinger, RC
人类病变和功能成像数据表明，杏仁核在处理负面刺激中发挥着重要作用。为了确定杏仁核在情感处理中的作用是否超出了负面刺激，受试者在接受功能磁共振成像时观看了情绪内容（积极Y和消极效价）和唤醒水平（高与低）不同的图片。杏仁核激活，相对于一个低唤醒和中性效价图片基线，显着增加积极和消极valenced刺激，并没有不同的两个效价。没有偏侧效应。虽然唤醒水平似乎调节杏仁核的反应，消极的刺激，所有积极的valenced图片（高和低的唤醒）产生显着的杏仁核反应。这些结果清楚地表明，杏仁核在处理情绪刺激方面的作用超出了消极和恐惧的刺激。NeuroReport 12：2779-2783（C）2001 Lippincott威廉姆斯和威尔金斯。
Human lesion and functional imaging data suggest a central role for the amygdala in the processing of negative stimuli. To determine whether the amygdala's role in affective processing extends beyond negative stimuli, subjects viewed pictures that varied in emotional content (positive Ys negative valence) and arousal level (high vs low) while undergoing functional magnetic resonance imaging. Amygdala activation, relative to a low arousal and neutral valence picture baseline, was significantly increased for both positively and negatively valenced stimuli and did not differ for the two valences. There were no laterality effects. Whereas arousal level appeared to modulate the amygdala response for negative stimuli, all positively valenced pictures (both high and low in arousal) produced significant amygdala responses. These results clearly demonstrate a role for the amygdala in processing emotional stimuli that extends beyond negative and fearful stimuli. NeuroReport 12:2779-2783 (C) 2001 Lippincott Williams & Wilkins.