Seizure length in electroconvulsive therapy as a function of age, sex, and treatment number
Seizure length in electroconvulsive therapy as a function of age, sex, and treatment number
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DOI：
10.1097/01.yct.0000263254.21668.f0
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发表时间：
2007-03-01
期刊：
影响因子：
2.5
通讯作者：
Rasmussen, Keith G.
中科院分区：
文献类型：
--
作者：
Rasimas, Joseph J.;Stevens, Susanna R.;Rasmussen, Keith G.
大多数电休克治疗(ECT)研究表明，癫痫发作的时间长短与临床疗效无关。然而，在实践中，如果发作持续时间似乎太短，临床医生通常会采取措施延长发作，尽管没有就ECT的最短发作持续时间达成普遍一致。我们认为，对于ECT领域来说，在一个非常大的队列中报告基于年龄和性别的治疗过程中的平均癫痫持续时间将是有用的，以提供参考标准。我们研究了519例患者的ECT过程，记录了治疗次数、性别、年龄以及运动和脑电发作持续时间。我们发现，女性癫痫发作的时间更长，但只在第一次治疗时。年龄与癫痫发作时间呈显著负相关。在一个疗程中，癫痫发作持续时间的最大下降发生在第一次治疗和第二次治疗之间；除此之外，癫痫发作持续时间保持相对恒定。
Most electroconvulsive therapy (ECT) research indicates that seizure length does not correlate with clinical efficacy. However, it is common in practice for clinicians to undertake measures to prolong seizures if the duration seems to be too short, although there is no universally agreed upon minimum seizure duration for ECT. We felt it would be informative for the ECT field to report mean seizure durations over the course of treatments based on age and sex in a very large cohort to provide norms for reference. We studied 519 patients' courses of ECT and recorded treatment number, sex, and age along with motor and electroencephalogram seizure duration. We found that women have longer seizures, but only at the first treatment session. There is a strong inverse correlation between age and seizure length. The biggest drop in seizure duration along a course of treatments occurs between the first and second treatments; beyond that, seizure duration remains relatively constant.