Biofeedback treatment for asthma
Biofeedback treatment for asthma
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DOI：
10.1378/chest.126.2.352
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发表时间：
2004-08-01
期刊：
影响因子：
9.6
通讯作者：
Habib, RH
中科院分区：
文献类型：
--
作者：
Lehrer, PM;Vaschillo, E;Habib, RH
研究目的：我们评估了心率变异性（HRV）生物反馈作为哮喘补充治疗的有效性。患者：94名成人门诊付费哮喘志愿者。设置：新泽西州医学和牙科大学罗伯特伍德约翰逊医学院的心理生理学实验室，以及参与哮喘医生的私人门诊办公室。干预措施：干预措施如下：（1）一个完整的协议（即，HRV生物反馈和腹式呼吸通过噘起嘴唇和延长呼气）;（2）HRV生物反馈单独;（3）安慰剂EEG生物反馈;和（4）一个等候名单control.Design：受试者首先使用控制药物预稳定，然后被随机分配到实验组。药物滴定每两周由盲哮喘专家根据国家心脏，肺，血液研究所指南的基础上，根据症状，肺活量测定，和家庭峰值flow.Measurements协议：受试者记录每日哮喘症状和每日两次呼气峰流量。在HRV和安慰剂生物反馈条件下，在每周一次的治疗前后进行肺量测定，在等待名单条件下，在每三周一次的评估会议上进行肺量测定。振荡电阻测量约triweekly.Results：与两个对照组相比，在两个HRV生物反馈组的受试者规定较少的药物，与两个积极的治疗之间的差异最小。改善平均为哮喘严重程度的一个完整水平。强迫振荡肺描记术的测量结果同样显示肺功能改善。安慰剂效应影响哮喘症状的改善，但不影响肺功能。组没有不同的发生严重的哮喘flares.Conclusions：结果表明，HRV生物反馈可能被证明是一个有用的辅助哮喘治疗，并可能有助于减少对类固醇药物的依赖。需要对该方法进行进一步评价。
Study objectives: We evaluated the effectiveness of heart rate variability (HRV) biofeedback as a complementary treatment for asthma.Patients: Ninety-four adult outpatient paid volunteers with asthma.Setting: The psychophysiology laboratory at The University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School, and the private outpatient offices of participating asthma physicians.Interventions: The interventions were as follows: (1) a full protocol (ie, HRV biofeedback and abdominal breathing through pursed lips and prolonged exhalation); (2) HRV biofeedback alone; (3) placebo EEG biofeedback; and (4) a waiting list control.Design: Subjects were first prestabilized using controller medication and then were randomly assigned to experimental groups. Medication was titrated biweekly by blinded asthma specialists according to a protocol based on National Heart, Lung, and Blood Institute guidelines, according to symptoms, spirometry, and home peak flows.Measurements: Subjects recorded daily asthma symptoms and twice-daily peak expiratory flows. Spirometry was performed before and after each weekly treatment session under the HRV and placebo biofeedback conditions, and at triweekly assessment sessions under the waiting list condition. Oscillation resistance was measured approximately triweekly.Results: Compared with the two control groups, subjects in both of the two HRV biofeedback groups were prescribed less medication, with minimal differences between the two active treatments. Improvements averaged one full level of asthma severity. Measures from forced oscillation pneumography similarly showed improvement in pulmonary function. A placebo effect influenced an improvement in asthma symptoms, but not in pulmonary function. Groups did not differ in the occurrence of severe asthma flares.Conclusions: The results suggest that HRV biofeedback may prove to be a useful adjunct to asthma treatment and may help to reduce dependence on steroid medications. Further evaluation of this method is warranted.