Postponing Childbearing and Fertility Preservation in Young Professional Women
Postponing Childbearing and Fertility Preservation in Young Professional Women
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DOI：
10.14423/smj.0000000000000789
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发表时间：
2018-04-01
影响因子：
1.1
通讯作者：
Rios, Julie
中科院分区：
文献类型：
--
作者：
Hurley, Emily G.;Ressler, Ilana B.;Rios, Julie
目的：评估年轻女性对卵巢储备功能测试和卵母细胞冷冻保存 (OC) 的认识，并评估卵巢储备功能测试如何影响保留生育能力的愿望。方法：在 20 岁及以上的女学生/年轻专业人员中进行了三项基于问卷调查的观察性研究。第三次调查在参与者接受抗缪勒氏管激素（AMH）测试后完成。测量的主要结果包括对 OC 可用的认识、对追求生育力保留的兴趣，以及兴趣是否会根据生育力下降的知识而改变。 结果：第一层研究包括对总共 337 名女性的调查。大多数女性受试者都知道 OC（92.1%）。大约 38.5% 的女性表示，她们会考虑使用 OC 来实现未来的生育目的。如果人们意识到自己的生育能力正在下降，这一比例就会增加到 60.3%。该研究的第二层包括 42 名住院医生/同事医生，他们接受了 AMH 测试。在测试完成之前和之后完成了一项调查。大约 12% 的参与者表示，他们的 AMH 水平改变了他们的预期生育年龄，而 24% 的参与者会根据结果考虑冷冻保存。关于 OC 最常见的担忧是成本。结论：应就生殖衰老和保留生育能力的选择向妇女提供咨询。提供卵巢储备测试并让 OC 更便宜可能会增加接受选择性 OC 的女性数量。
Objectives: To evaluate young women's awareness of ovarian reserve testing and oocyte cryopreservation (OC) and assess how testing ovarian reserve may affect the desire for fertility preservation.Methods: Three questionnaire-based observational studies were conducted among female students/young professionals 20 years of age and older. The third survey was completed after participants were offered anti-Mullerian hormone (AMH) testing. The main outcomes measured included awareness that OC is available, interest in pursuing fertility preservation, and whether interest would change based on knowledge of declining fertility.Results: The first tier of the study included a survey of a total of 337 women. The majority of female subjects were aware of OC (92.1%). Approximately 38.5% of the women responded that they would consider OC for future fertility purposes. This percentage increased to 60.3% if one was aware her fertility was declining. The second tier of the study included 42 resident/fellow physicians who were offered AMH testing. A survey was completed before and after testing was completed. Approximately 12% of participants stated that their AMH level altered their anticipated age of childbearing, whereas 24% would consider cryopreservation based on their results. The most common concern regarding OC was the cost.Conclusions: Women should be counseled regarding reproductive aging and options for fertility preservation. Offering ovarian reserve testing and making OC more affordable may increase the number of women who undergo elective OC.