Melanogenesis in Cryptococcus neoformans.

Melanogenesis in Cryptococcus neoformans.
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新型隐球菌中的黑色素生成。

DOI:
10.1099/00221287-134-4-1037
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发表时间:
1988
期刊:
Journal of general microbiology
影响因子:
--
通讯作者:
K. Kwon
K. Kwon
中科院分区:
--
文献类型:
--
作者:
Itzhack Polacheck;K. Kwon

文献摘要

被引文献

相似文献

新型隐球菌中的黑素生成开始于苯酚氧化酶对二羟基苯丙氨酸的氧化。后续步骤非常迅速。用高效液相色谱法分离和鉴定了两个中间体多巴色素和5,6-二羟基吲哚。C.黑色素形成的途径。根据这些中间体的存在,提出了neoformans。
Melanogenesis in Cryptococcus neoformans begins with the oxidation of dihydroxyphenylalanine by the enzyme phenol oxidase. The succeeding steps are very rapid. Two intermediates, dopachrome and 5,6-dihydroxyindole, have been isolated and characterized by high performance liquid chromatography. A pathway of melanin formation in C. neoformans is proposed, based on the presence of these intermediates.