Spatial integration of cold pressor pain sensation in humans
Spatial integration of cold pressor pain sensation in humans
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DOI：
10.1016/j.neulet.2003.12.060
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发表时间：
2004-05-06
影响因子：
2.5
通讯作者：
Pertovaara, A
中科院分区：
文献类型：
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作者：
Martikainen, IK;Närhi, MV;Pertovaara, A
通过测量冰水诱发的第一次痛觉的潜伏期，在有和没有条件性冷加压痛（CPP）的情况下，研究了健康人手部CPP的空间整合。单独的CPP显示出明显的空间总和效应。当调节和测试CPP同时应用时，调节CPP抑制测试CPP在邻近和远端部位。当测试CPP应用后，条件CPP（即由条件CPP诱导的疼痛是相当强的比测试CPP诱发）条件CPP抑制测试CPP仅在一个遥远的网站，但增强它在邻近网站。测试刺激面积的减少增加了条件性CPP的抑制作用。因此，CPP显示空间总和或抑制，这取决于实验参数。(C)2003爱思唯尔爱尔兰有限公司保留所有权利。
Spatial integration of cold pressor pain (CPP) in the hand was studied in healthy human subjects by measuring the latency to the ice water-induced first pain sensation with and without conditioning CPP. CPP alone showed a marked spatial summation effect. When conditioning and test CPP were applied at the same time, conditioning CPP suppressed test CPP both in an adjacent and a distant site. When test CPP was applied after the conditioning CPP (i.e. pain induced by conditioning CPP was considerably stronger than that evoked by test CPP) conditioning CPP suppressed the test CPP only in a distant site but enhanced it in an adjacent site. A decrease in the test stimulus area increased the suppressive effect by conditioning CPP. Thus, CPP shows spatial summation or inhibition depending on experimental parameters. (C) 2003 Elsevier Ireland Ltd. All rights reserved.