Reusable localized surface plasmon sensors based on ultrastable nanostructures.
Reusable localized surface plasmon sensors based on ultrastable nanostructures.
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DOI：
10.1002/smll.200900497
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发表时间：
2010-01
期刊：
影响因子：
13.3
通讯作者：
N. Vogel;Mathieu Jung;N. Bocchio;M. Retsch;M. Kreiter;Ingo Köper
中科院分区：
文献类型：
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作者：
N. Vogel;Mathieu Jung;N. Bocchio;M. Retsch;M. Kreiter;Ingo Köper
通过纳米球光刻产生的纳米颗粒阵列被广泛用于传感应用，因为它们的局部表面等离子体共振对局部介电环境的变化极其敏感。常规生产的颗粒阵列的任何生物定向传感应用的主要缺点是纳米颗粒在水性介质和缓冲溶液中缺乏稳定性。在这里，一个强大的和可重复使用的纳米级传感平台的基础上嵌入在二氧化硅矩阵的金纳米粒子的局部表面等离子体共振。该结构在水性环境中表现出极高的稳定性，并且可以通过简单的表面机械清洁进行多次再生。平台表面设计为超平，因此使其成为任何生物传感应用的理想基底。
Nanoparticle arrays created by nanosphere lithography are widely used in sensing applications since their localized surface plasmon resonances are extremely sensitive to changes in the local dielectric environment. A major drawback for any biologically oriented sensing application of conventionally produced particle arrays is the lack of stability of the nanoparticles in aqueous media and buffer solutions. Here, a robust and reusable nanoscale sensing platform based on localized surface plasmon resonances of gold nanoparticles embedded in a silicon dioxide matrix is presented. The architecture exhibits extremely high stability in aqueous environments and can be regenerated several times by simple mechanical cleaning of the surface. The platforms surface is ultraflat by design, thus making it an ideal substrate for any bio-oriented sensing application.