Tai Chi for Overweight/Obese Adolescents and Young Women with Polycystic Ovary Syndrome: A Randomized Controlled Pilot Trial.
Tai Chi for Overweight/Obese Adolescents and Young Women with Polycystic Ovary Syndrome: A Randomized Controlled Pilot Trial.
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太极拳治疗超重/肥胖青少年和患有多囊卵巢综合症的年轻女性：一项随机对照试点试验
DOI：
10.1155/2022/4291477
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发表时间：
2022
影响因子：
--
通讯作者：
Hou, Lihui
中科院分区：
文献类型：
--
作者：
Li, Yan;Peng, Changle;Zhang, Meiwei;Xie, Liangzhen;Gao, Jinjin;Wang, Yingji;Gao, Yuanhe;Hou, Lihui
运动是多囊卵巢综合征(PCOS)推荐的干预措施之一，目前的证据表明，太极可能有良好的效果。这项随机对照试验的目的是研究太极治疗超重/肥胖青少年和患有多囊卵巢综合征的年轻女性的可行性和潜在效果，以便更好地设计和实施未来的确定性随机对照试验(RCT)。将50例患者随机分为太极拳和运动自我监测两组，干预时间为3个月，干预时间为3个月，评价干预的可行性和有效性。 ： 2。共有42名患者完成了研究，其中太极组24人，对照组18人。与自我监测运动组相比，经基线体重指数调整后的太极组体重指数(BMI)显著下降。与对照组相比，睾酮水平和血脂水平也有所下降；胰岛素抵抗的稳态模型评估(HOMA-IR)也有同样的趋势，但差异没有统计学意义。太极组24名患者(满分30名，80%)和自我监测运动组18名患者(满分20名，90%)完成数据收集。两组共进行了36次锻炼。太极组患者平均参加 ± 2.21节课(93.06%)，自我监控运动组参加32节 ± 3.06节(88.27%)。目前的先导性研究是可行的；太极组在3个月时多囊卵巢综合征患者的体重指数、睾酮水平和血脂水平都有所下降。在未来的最终试验中，较低的招募比率和结果测量导致患者接受性较差，例如需要考虑5时间点口服葡萄糖耐量试验，还需要一种固定类型的有氧运动和对照组研究人员的监督。试验注册：ClinicalTrials.gov，NCT02608554。
Exercise is one of the recommended interventions for polycystic ovary syndrome (PCOS), and current evidence has shown that Tai chi may have favorable effects. The objective of this randomized controlled pilot trial was to study the feasibility and potential effects of Tai chi for overweight/obese adolescents and young women with PCOS, so a future definitive randomized controlled trial (RCT) can be well designed and implemented. This study recruited 50 patients who were randomly assigned to two groups (Tai chi and self-monitored exercise) at a ratio of 3 : 2. The intervention lasted for 3 months, and the feasibility and effectiveness outcomes were measured. A total of 42 patients completed the study, including 24 in the Tai chi group and 18 in the control group. Compared with the self-monitored exercise group, there was a significantly decreased body mass index (BMI) in the Tai chi group adjusted for baseline BMI. The testosterone level and lipid profile were also decreased compared to controls; the same tendency was also observed for the homeostasis model assessment of insulin resistance (HOMA-IR), but the difference did not achieve statistical significance. Twenty-four (out of 30, 80%) patients in the Tai chi group and 18 (out of 20, 90%) patients in the self-monitored exercise group completed the data collection. A total of 36 exercise sessions were held in both groups. Patients in the Tai chi group took a mean of 34.0 ± 2.21 classes (93.06%), and those in the self-monitored exercise group engaged in 32 ± 3.06 exercise sessions (88.27%) out of the 36 required exercise sessions. The present pilot study was feasible to deliver; there was a decrease in BMI, testosterone level, and lipid profile for PCOS patients in the Tai chi group at 3 months. In a future definitive trial, lower recruitment rate and outcome measurements lead to poor patient acceptance such as the 5-time point oral glucose tolerance test need to be considered and one fixed type of aerobic exercise and supervision from the investigator for the control group are also needed. Trial registration: ClinicalTrials.gov, NCT02608554.
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影响因子：
2.5
作者：
Li Y;Peng C;Cao G;Li W;Hou L
通讯作者：
Hou L
影响因子：
81.5
作者：
Azziz, Ricardo;Carmina, Enrico;Yildiz, Bulent O.
通讯作者：
Yildiz, Bulent O.
影响因子：
8.1
作者：
Chan, Aileen Wai Kiu;Chair, Sek Ying;Taylor-Piliae, Ruth E.
通讯作者：
Taylor-Piliae, Ruth E.
影响因子：
4.2
作者：
Lin, Shu-Fen;Sung, Huei-Chuan;Smith, Graeme D.
通讯作者：
Smith, Graeme D.
DOI：
10.1155/2021/6699935
发表时间：
2021
期刊：
Evidence-based complementary and alternative medicine : eCAM
影响因子：
--
作者：
Liu YN;Wang L;Fan X;Liu S;Wu Q;Qian YL
通讯作者：
Qian YL