Recent advances in the use of chiral metal complexes with achiral ligands for application in asymmetric catalysis
Recent advances in the use of chiral metal complexes with achiral ligands for application in asymmetric catalysis
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DOI：
10.1039/c5cy00182j
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发表时间：
2015-01-01
影响因子：
5
通讯作者：
Zhou, Feng
中科院分区：
文献类型：
--
作者：
Cao, Zhong-Yan;Brittain, William D. G.;Zhou, Feng
这一观点介绍了最近的进展，在不对称催化与手性的金属配合物显示Delta/Delta对映异构体的配体内的中心手性的情况下，重点放在Ir（III）和Rh（III）系统。这些配合物在不对称催化反应中表现出了良好的选择性，包括氢键给体-受体催化、仲胺或Bronsted碱氢键给体双功能催化、刘易斯酸催化和光氧化还原催化等。这一观点强调了拓宽领域的手性在金属催化，并提出了一个选择的不对称转换已成功地进行了使用它们。
This perspective describes recent progress in asymmetric catalysis with chiral only-at-metal complexes displaying Delta/Delta enantiomorphs in the absence of central chirality within the ligands, with an emphasis on Ir(III) and Rh(III) systems. The good selectivity achieved when using these complexes in asymmetric catalysis has been demonstrated in asymmetric transformations through various mechanisms, including hydrogenbond donor-acceptor, secondary amine or Bronsted base hydrogen-bond donor bifunctional catalysis, Lewis acid and photoredox catalysis under mild reaction conditions. This perspective highlights the widening field of chiral-at-metal catalysis and presents a selection of asymmetric transformations which have been successfully carried out using them.