Foot-and-mouth disease vaccines
Foot-and-mouth disease vaccines
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DOI：
10.1016/j.vetmic.2016.12.018
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发表时间：
2017-07-01
影响因子：
3.3
通讯作者：
de los Santos, Teresa
中科院分区：
文献类型：
--
作者：
Diaz-San Segundo, Fayna;Medina, Gisselle N.;de los Santos, Teresa
口蹄疫（FMD）是偶蹄动物的一种高度传染性疾病。这种疾病影响世界许多地区，经常在牲畜（主要是养殖牛和猪）中引起广泛的流行病，尽管绵羊、山羊和许多野生物种也很容易感染。在粮食和农场动物对自给农业至关重要的国家，口蹄疫的爆发严重影响粮食安全和发展。在高度工业化的发达国家，口蹄疫流行造成经济和社会破坏，这主要是由于遵守世界动物卫生组织 (OIE) 采取的卫生措施。口蹄疫发病率高、宿主范围复杂、遗传多样性广泛，使得口蹄疫防控工作异常艰巨。在本文中，我们回顾了多年来开发的多种疫苗方法，最终旨在成功控制和根除这种可怕的疾病。由 Elsevier B.V. 出版
Foot-and-mouth disease (FMD) is a highly contagious disease of cloven-hoofed animals. The disease affects many areas of the world, often causing extensive epizootics in livestock, mostly farmed cattle and swine, although sheep, goats and many wild species are also susceptible. In countries where food and farm animals are essential for subsistence agriculture, outbreaks of FMD seriously impact food security and development. In highly industrialized developed nations, FMD endemics cause economic and social devastation mainly due to observance of health measures adopted from the World Organization for Animal Health (OIE). High morbidity, complex host-range and broad genetic diversity make FMD prevention and control exceptionally challenging. In this article we review multiple vaccine approaches developed over the years ultimately aimed to successfully control and eradicate this feared disease. Published by Elsevier B.V.