Synthesis of enantiomerically pure 3-fluoromethylthreonines from (S)-1-fluoro-3-tolylsulfinylacetone
Synthesis of enantiomerically pure 3-fluoromethylthreonines from (S)-1-fluoro-3-tolylsulfinylacetone
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DOI：
10.1039/cc9960002569
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发表时间：
1996-11-21
影响因子：
4.9
通讯作者：
Sidoti, G
中科院分区：
文献类型：
--
作者：
Arnone, A;Gestmann, D;Sidoti, G
The copper(I) catalysed aldol reaction between methyl isocyanoacetate and (S)-3-fluoro-1-(4-methylphenyl)-sulfinylacetone affords oxazoline products which, after diastereoisomer separation, give in high yields optically pure 3-fluoromethylthreonine analogues whose absolute and relative configurations have been assigned through X-ray analyses.
